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Dry Eye Disease clinical trials

View clinical trials related to Dry Eye Disease.

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NCT ID: NCT03292809 Completed - Dry Eye Disease Clinical Trials

CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease (DED)

Start date: October 19, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

The objective of this study is to assess the efficacy, safety, and tolerability of CyclASol Ophthalmic Solution in comparison to vehicle for the treatment of the signs and symptoms of DED.

NCT ID: NCT03291704 Not yet recruiting - Dry Eye Disease Clinical Trials

Investigating the Effect of At Home Thermal Therapy on Dry Eye Patients With Meibomian Gland Dysfunction

Start date: March 2018
Phase: N/A
Study type: Interventional

The purpose of this pilot study is to determine the feasibility of at home thermal therapy with a wireless, portable device, as an effective management of Meibomian Gland Dysfunction. This will be done by assessing patients for improvement in symptoms and ocular oil gland function after 4 weeks of a daily thermal therapy application.

NCT ID: NCT03287635 Completed - Dry Eye Disease Clinical Trials

Clinical Efficacy of H.P. Acthar Gel 80 U/ml to Improve the Signs and Symptoms in Subjects With Dry Eye Disease

Start date: July 1, 2018
Phase: Phase 4
Study type: Interventional

Study Title: A Phase 4 Study to Assess the Clinical Efficacy of H.P. Acthar Gel 80 U/ml to Improve the Signs and Symptoms in Subjects with Dry Eye Disease

NCT ID: NCT03216096 Completed - Dry Eye Disease Clinical Trials

Assessing Safety and Efficacy of DE-089 Ophthalmic Solution in Patients With Dry Eye Disease

Start date: September 8, 2017
Phase: Phase 1
Study type: Interventional

The objective of this study is to assess safety and efficacy of DE-089 ophthalmic solution in patients with dry eye disease in Taiwan.

NCT ID: NCT03108664 Completed - Dry Eye Disease Clinical Trials

HELIX, a Double-masked Study of SYL1001 in Patients With Moderate to Severe Dry Eye Disease (DED)

Start date: May 18, 2017
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether SYL1001 ophthalmic solution is safe and effective in the treatment of signs and symptoms of Dry Eye Disease.

NCT ID: NCT03048526 Completed - Dry Eye Disease Clinical Trials

Influence of Perfluorohexyloctane (NovaTears) on Tear Film Thickness in Patients With Mild to Moderate Dry Eye Disease

Start date: December 15, 2016
Phase: N/A
Study type: Interventional

Patients with mild to moderate dry eye disease will be randomized to receive either NovaTears® or Hydrabak® eye drops as control.

NCT ID: NCT02943382 Not yet recruiting - Dry Eye Disease Clinical Trials

Fingerprick Autologous Blood (FAB) in Mebomian Gland Dysfunction (MGD)

Start date: November 2016
Phase: N/A
Study type: Interventional

Dry eye disease remains one of the most common complaints seen in ophthalmic clinics. Causes of dry eye are multifactorial, with the most common cause of evaporative dry eye disease being meibomian gland dysfunction (MGD). Fingerprick autologous blood (FAB) is a novel method which uses a patient's own blood to treat dry eye conditions.

NCT ID: NCT02848222 Completed - Dry Eye Disease Clinical Trials

Pilot Study for Investigating the Effect of the Bruder Eye Hydrating Compress on Contact Lens Discomfort in Contact Lens Wearers

Start date: July 2016
Phase: N/A
Study type: Interventional

The purpose of this prospective study is to evaluate the benefits of using the Bruder Moist Heat Compress in contact lens wearers who report reduced comfortable wear time. This will be done by assessing for improvement in ocular oil gland function and comfortable contact lens wearing time after one month of daily warm compress application. The efficacy of the Bruder Moist Heat Compress applied once will be compared to twice daily application as well as compared to warm compress application using a wash cloth.

NCT ID: NCT02831387 Terminated - Dry Eye Disease Clinical Trials

Evaluation of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease

Start date: July 2016
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effect of treatment with 0.017% P-321 on Dry Eye Symptoms.

NCT ID: NCT02824913 Terminated - Dry Eye Disease Clinical Trials

Study of the Pharmacodynamic Activity of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease

Start date: July 2016
Phase: Phase 2
Study type: Interventional

The purpose of this Phase 2a study is to assess changes in tear volume by the non-invasive techniques Ultra High Resolution Optical Coherence Tomography (UHR-OCT) following the administration of P-321 Ophthalmic Solution or Placebo in subjects with tear deficient dry eye disease.