Clinical Trials Logo

Dry Eye Disease clinical trials

View clinical trials related to Dry Eye Disease.

Filter by:

NCT ID: NCT01421498 Completed - Dry Eye Disease Clinical Trials

Safety and Efficacy Study of SAR 1118 to Treat Dry Eye Conducted in a Controlled Adverse Environment (CAE) (OPUS-1)

OPUS-1
Start date: August 29, 2011
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the efficacy of SAR 1118 Ophthalmic Solution (5.0%) compared to placebo in the treatment of Dry Eye. The safety and tolerability of SAR 1118 Ophthalmic Solution (5.0%) compared to placebo in subjects with dry eye when administered BID for 12 weeks will also be evaluated.

NCT ID: NCT01321424 Completed - Dry Eye Disease Clinical Trials

Diurnal Variation in Tear Osmolarity

Start date: March 2011
Phase: N/A
Study type: Observational

The purpose of this study is to measure the change in Tear Osmolarity during the course of the day to support clinical diagnosis of aqueous deficiency or meibomian gland disease and differentiate between the two forms of dry eye.

NCT ID: NCT01276223 Completed - Dry Eye Disease Clinical Trials

Evaluation of Anti-Inflammatory Treatment in Dry Eye Patients

Start date: February 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study was to determine if difluprednate ophthalmic emulsion is effective in reducing the ocular symptoms of dry eye disease, as measured by a global Visual Analog Scale (VAS) discomfort score.

NCT ID: NCT01014078 Completed - Dry Eye Disease Clinical Trials

A Four Week Study of Azithromycin Ophthalmic Solution, 1% Versus Placebo in Subjects With Dry Eye Disease

Start date: October 2009
Phase: Phase 4
Study type: Interventional

The objective of this study is to compare the safety and efficacy of azithromycin ophthalmic solution, 1% in dry eye subjects over a four week treatment period, using placebo as a comparison.

NCT ID: NCT00831662 Completed - Dry Eye Disease Clinical Trials

The Effects of Diquafosol Tetrasodium Ophthalmic Solution, 2% in Subjects With Dry Eye Disease (P08637)

Start date: January 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to confirm the safety and efficacy of diquafosol tetrasodium ophthalmic solution, 2% vs. placebo, in subjects with dry eye disease.

NCT ID: NCT00827255 Completed - Dry Eye Disease Clinical Trials

Physician's Evaluation of Cyclosporine Ophthalmic Emulsion 0.05%

Start date: January 2009
Phase:
Study type: Observational

The objective of this retrospective chart review is to evaluate the patient characteristics, treatment variations and efficacy of a second trial of Cyclosporine Ophthalmic Emulsion 0.05% therapy in chronic dry eye patients who were initially treated with Cyclosporine Ophthalmic Emulsion 0.05% but discontinued use after less than 12 weeks of treatment.

NCT ID: NCT00799682 Completed - Dry Eye Disease Clinical Trials

Exploratory Study Comparing Signs and Symptoms in Patients With Ocular Hypertension or Glaucoma Using Xalatan R® or Travatan Z®

Start date: October 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if there is a difference in the ocular signs and symptoms of subjects' eyes using Xalatan® 0.005% versus Travatan Z® 0.004% based on the outcome of subject assessment and clinical assessment in patients with Ocular Hypertension or Glaucoma with mild to moderate dry eye at baseline in accordance with the Oxford Grading Scale.

NCT ID: NCT00760045 Completed - Dry Eye Disease Clinical Trials

Clinical Pharmacological Study of AL-43546 Ophthalmic Product in Subjects With Shortened Tear Film Break Up Time

Start date: August 2008
Phase: Phase 2
Study type: Interventional

The purpose of the study is to observe lacrimal fluid condition (tear film break-up time) chronologically after a single dose of AL-43546 ophthalmic products(0.15%, 0.25% and vehicle)and 0.1% sodium hyaluronate ophthalmic solution and compare lacrimal fluid retention time between them.

NCT ID: NCT00758784 Completed - Dry Eye Disease Clinical Trials

Safety and Efficacy of an Ophthalmic Solution in Dry Eye Disease

Start date: August 13, 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the safety and efficacy of an ophthalmic solution in dry eye disease.

NCT ID: NCT00680108 Completed - Dry Eye Disease Clinical Trials

A Study to Determine the Safety and Tolerability of Escalating Doses of INS365 Ophthalmic Solution

Start date: September 1999
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of INS365 Ophthalmic Solution when applied topically as eyedrops in patients with mild to moderate dry eye disease.