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Dry Eye Disease clinical trials

View clinical trials related to Dry Eye Disease.

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NCT ID: NCT06444516 Not yet recruiting - Dry Eye Disease Clinical Trials

Study of Safety and Performance of a Novel Ocular Lubricant in Subjects With Dry Eye Disease

Start date: August 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate and demonstrate the efficacy and safety of an investigational ocular lubricant formulation in patients with mild to moderate dry eye disease (DED).

NCT ID: NCT06443554 Recruiting - Dry Eye Disease Clinical Trials

Evaluation of the Effectiveness of a Community Health Management Program for Dry Eye Disease in Middle-Aged and Elderly Individuals

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

This study evaluates the effectiveness of a community health management program for middle-aged and elderly patients with dry eye disease (DED). By comparing the community-based health management plan with conventional treatment, the study aims to determine the impact on eye health and quality of life.

NCT ID: NCT06424444 Recruiting - Dry Eye Disease Clinical Trials

A Clinical Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease

Start date: April 29, 2024
Phase: Phase 3
Study type: Interventional

A Multicenter, Phase 3, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Environment Exposure Clinical Trial to Assess the Efficacy and Safety of 0.25% Reproxalap

NCT ID: NCT06400459 Not yet recruiting - Dry Eye Disease Clinical Trials

IVW-1001 Phase 1/2 in Subjects With Dry Eye Disease

Start date: July 1, 2024
Phase: Phase 1/Phase 2
Study type: Interventional

Double-masked, dose-response, trial of IVW-1001 in subjects with dry eye disease.

NCT ID: NCT06389214 Completed - Dry Eye Disease Clinical Trials

A Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease

Start date: April 9, 2024
Phase: Phase 3
Study type: Interventional

A Randomized, Double-Masked, Vehicle-Controlled Parallel Group Clinical Trial to Assess Efficacy and Safety of 0.25% Reproxalap Ophthalmic Solution Compared to Vehicle in Subjects with Dry Eye Disease

NCT ID: NCT06375343 Not yet recruiting - Dry Eye Disease Clinical Trials

Study to Evaluating PRO-240 Ophthalmic Solution Compared to Optive®

Start date: October 30, 2024
Phase: Phase 1
Study type: Interventional

This is a phase I clinical study to evaluating safety and tolerability of PRO-240 ophthalmic solution through the incidence of unexpected adverse events, as well as through changes in Best Corrected Visual Acuity (BCVA), and the incidence of stinging after its administration, compared to Optive®.

NCT ID: NCT06370585 Not yet recruiting - Dry Eye Disease Clinical Trials

Clinical Study to Evaluate the Safety and Tolerability of PRO-229 Ophthalmic Solution Compared to Lagricel® Ofteno PF

Start date: May 30, 2024
Phase: Phase 1
Study type: Interventional

This is a phase I study evaluating safety and tolerability of PRO-229 ophthalmic solution through he incidence of unexpected adverse events, changes in Best Corrected Visual Acuity (BCVA), incidence of chemosis, and changes in ocular surface staining using the Sjögren's International Collaborative Clinical Alliance (SICCA) Ocular Staining Score (OSS) scale compared to Lagricel® Ofteno PF in clinically healthy subjects.

NCT ID: NCT06370039 Recruiting - Dry Eye Disease Clinical Trials

Study of INV-102 Ophthalmic Solution in Adults With Moderate to Severe Dry Eye Disease

Start date: March 27, 2024
Phase: Phase 2
Study type: Interventional

Phase 2 study to assess the efficacy of topically administered eyedrops of INV-102 during 4-week repeat dosing in subjects with moderate to severe dry eye disease.

NCT ID: NCT06349356 Recruiting - Dry Eye Disease Clinical Trials

Prospective Evaluation of Efficacy and Safety of an Intense Pulsed Light Device to Treat Dry Eye Disease"

Start date: March 28, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the efficacy and safety of C.STIM, an intense pulsed light device to treat signs and symptoms of dry eye disease. The main question it aims to answer is: • Difference of the evolution of Tear Break-Up time (TBUT) between the 2 arms of the study (placebo and treated). Researchers will compare treated group and placebo to respond to the main question. Participants will assess to an inclusion visit (disease evaluation purpose) and then four IPL treatment visit to finish with the last visit (disease evaluation purpose).

NCT ID: NCT06329791 Not yet recruiting - Dry Eye Disease Clinical Trials

A Phase 3 Study to Evaluate AZR-MD-001 in Patients With Abnormal Meibomian Gland Function and Dry Eye Disease (DED)

Start date: May 2024
Phase: Phase 3
Study type: Interventional

This study is a multicenter, double-masked, vehicle-controlled, randomized, parallel group study designed to evaluate the treatment of abnormal meibomian gland function and associated symptoms of DED using either AZR-MD-001 0.5% ophthalmic ointment or its vehicle. Study drug (either AZR-MD-001 or vehicle) will be dosed twice-weekly at bedtime for up to 12 months.