Substance Use Disorders Clinical Trial
Official title:
A Randomized Trial of CBT4CBT for Women in Residential Treatment for Substance Use Disorders
This project examines computer-delivered cognitive-behavioral intervention (CBT4CBT) as an adjunct to residential treatment for women with substance use disorders (SUD). The project will conduct a 2-arm randomized clinical trial (RCT) comparing post-discharge relapse rates for treatment as usual (TAU) with access to the CBT4CBT program vs. TAU in a residential sample of women with SUDs.
Women with substance use disorders face unique barriers to substance use treatment, and as a
result, are less likely to seek treatment for substance use than their male counterparts.
Women's residential treatment settings have been shown to have higher rates of treatment
completion and better outcomes; however, relapse rates for substance use are high, with
estimates ranging from 40-60%. Cognitive behavioral therapy (CBT) has been identified as an
evidence-based treatment known to improve relapse rates by teaching clients how to recognize
and respond to their cues for substance use. Women may particularly benefit from CBT, as
their relapse risk factors include depression, interpersonal stress, and relationship
conflict.
Despite the effectiveness of CBT, its dissemination is hindered due to limited availability
of trained clinicians, cost, and limited resources. Computer-based training for cognitive
behavioral therapy (CBT4CBT) offers an opportunity to improve the quality and reach of
treatment services that is both feasible and cost-effective. Studies to date have
demonstrated the utility of CBT4CBT in outpatient settings; however, it has not yet been
evaluated as an adjunct to residential treatment for SUDs.
The specific aims are to: 1) Examine feasibility for use of CBT4CBT in a residential
treatment program for women with SUDs; 2) Conduct a small RCT comparing TAU with access to
the CBT4CBT program (CBT4CBT; intervention) vs. treatment as usual (TAU; control) using
relapse rates and days of use as primary treatment outcomes; 3) Exploratory analyses will
identify other correlates (e.g., coping strategies, depression) of relapse at 4 and 12 weeks
post-discharge.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT05660434 -
Using Aromatherapy in Substance Use Disorder
|
N/A | |
Active, not recruiting |
NCT05338268 -
Substance Use and Loneliness
|
N/A | |
Completed |
NCT04098614 -
Barriers to Substance Use Disorder Recovery
|
N/A | |
Completed |
NCT03954184 -
E-health Implementation (Iowa)
|
N/A | |
Completed |
NCT03590106 -
Cardiac Surgery Peer Recovery Support Program
|
N/A | |
Recruiting |
NCT05118204 -
Randomized Trial of Buprenorphine Microdose Inductions During Hospitalization
|
Phase 4 | |
Recruiting |
NCT06273228 -
Parenting Young Children in Pediatrics
|
N/A | |
Recruiting |
NCT05327504 -
Written Exposure Therapy for Veterans With SUD and PTSD
|
N/A | |
Terminated |
NCT03517111 -
The Impact of a Parenting Intervention on Latino Youth Health Behaviors
|
N/A | |
Completed |
NCT04284813 -
Families With Substance Use and Psychosis: A Pilot Study
|
N/A | |
Completed |
NCT04401215 -
Technologically-Augmented Referrals to Mitigate Addiction Consequences
|
N/A | |
Not yet recruiting |
NCT06163651 -
Evaluating a One-Year Version of the Parent-Child Assistance Program
|
N/A | |
Not yet recruiting |
NCT06187701 -
Co-Active Therapeutic Theatre (Co-ATT) for Dual-Diagnosis Patients
|
N/A | |
Recruiting |
NCT04296604 -
Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations
|
N/A | |
Active, not recruiting |
NCT02382042 -
Intensive Referral Intervention to Improve Substance Use Disorder Treatment Outcomes Among Rural and Highly Rural Veterans
|
N/A | |
Completed |
NCT01237366 -
Study Targeting Affect Regulation
|
Phase 1/Phase 2 | |
Terminated |
NCT01356667 -
Drum-Assisted Therapy for Native Americans
|
N/A | |
Completed |
NCT00708890 -
Twelve Step Based Self-help Groups for Substance Related Disorders
|
N/A | |
Active, not recruiting |
NCT04048850 -
Zepatier in Patients With Substance Use
|
||
Recruiting |
NCT05976646 -
Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion
|
Phase 1/Phase 2 |