Ertapenem Versus Meropenem/Imipenem for ESBL+ Gram-negative Infections

Status Recruiting

Clinical Trial Summary

Adult patients with ESBL-producing Gram negative infections are randomized to receive ertapenem or meropenem/imipenem. Clinical and microbiological responses between both groups are compared.

Clinical Trial Description

Ertapenem is active against ESBL-producing Gram negative bacteria. This study is conducted to determine if ertapenem is effective against ESBL-producing Gram negative infections similar to meropenem/imipenem. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Drug Safety
Gram-Negative Bacterial Infections

Clinical Trial Details

NCT number	NCT01297842
Study type	Interventional
Source	Mahidol University
Contact	Visanu Thamlikitkul, MD
Phone	6624125994
Email	sivth@mahidol.ac.th
Status	Recruiting
Phase	Phase 4
Start date	May 2011
Completion date	August 2013

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT01425502` - Data-driven Quality Improvement in Primary Care - Trial	N/A
Recruiting	`NCT01756183` - Exploratory Study on the S-1 + Paclitaxel Chemotherapy for Unresectable Gastric Cancer	Phase 2
Completed	`NCT01757860` - Safety and Pharmacokinetics Study of CARD-024 in Healthy Subjects	Phase 1
Completed	`NCT01355016` - A Trial to Assess the Safety, Tolerability, and Pharmacokinetics of MDT-637 in Healthy Volunteers	Phase 1
Completed	`NCT01179854` - Remegal Different Doses in Patients With Refractory Partial Seizures	Phase 2
Completed	`NCT00376415` - A Safety Study of Lessertia Frutescens in Adults.	Phase 1
Active, not recruiting	`NCT01722916` - Reducing and Removing Hyaluronic Acid Filler With Hyaluronidase	Early Phase 1
Completed	`NCT01727778` - Safety and Preliminary Efficacy Study of the Antibody PAT-SM6 in Patients With Relapsed or Refractory Multiple Myeloma	Phase 1
Completed	`NCT01475097` - Comparing Patient Comfort and Safety Between Iodixanol and Iopamidol in Patients Undergoing Peripheral Arteriography	Phase 4
Completed	`NCT01412658` - Clinical Safety of a Novel Milk Protein Peptide	Phase 1
Terminated	`NCT01847222` - An Assessment of the Safety and Pharmacokinetics of Ascending Doses of SANGUINATE™ in Healthy Volunteers.	Phase 1
Unknown status	`NCT01633099` - Therapeutic Effect and Safety Study of Decitabine in Elderly Acute Myeloid Leukemia Patients	Phase 3
Completed	`NCT01284582` - Safety, Immunogenicity and Dose Response of ATH03, a New Vaccine Against the Cholesterol Ester Transfer Protein (CETP)	Phase 1
Completed	`NCT01556607` - A Trial to Assess the Safety, Tolerability and Pharmacokinetics of MDT-637 in Subjects With Intermittent, or Mild-to-Moderate Persistent, Asthma	Phase 1
Completed	`NCT01557270` - Efficacy and Safety Study of Dexmedetomidine as an Additive to Local Anesthetics in Shoulder Surgery	Phase 3
Completed	`NCT01319903` - Clinical Assessment of Safety and Tolerability of the New Monoclonal Humanized Antibody CaCP29	Phase 1
Completed	`NCT01271569` - A Study to Assess the Efficacy and Safety of Fospropofol Disodium	Phase 1
Recruiting	`NCT04785027` - Comparison of PSORI-CM01 Formula vs Gu Ben Hua Yu Formula Combined With AD-MSCs in Psoriasis	Phase 1/Phase 2
Completed	`NCT01428882` - Propofol vs. Midazolam-based Balanced Propofol for Nonanesthesiologist Moderate Sedation in Colonoscopy	Phase 4
Completed	`NCT01367873` - Ascending Single-Dose Study to Evaluate VIA-3196 in Healthy Subjects	Phase 1