Clinical Characteristics for the Critical Ill Patients With Klebsiella Pneumoniae Infection

Drug Resistance Clinical Trial

Official title:

Analysis of the Clinical Characteristics for the Critical Ill Patients With Klebsiella Pneumoniae Infection: A Multi-center Research in the Intensive Care Units

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04404582
• Other study ID #: K2019-06-031
• Status: Completed
• Start date: January 1, 2015
• Est. completion date: February 28, 2020

Study information

• Verified date: May 2020
• Source: Fujian Provincial Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The detection of Klebsiella pneumoniae virulence gene and antibiotics resistance gene takes a long time and high cost with equipment requirements. Distinguishing the Klebsiella pneumoniae by gene were late for clinical treatment. Therefore, the investigators aim to study the clinical characteristics of critically ill patients with Klebsiella pneumoniae infection which expressed different drug sensitivity test results.

Description:

Clinical data of adult patients in integrated ICUs of 6 hospitals of Fujian Province China from January 2015 to July 2019 were collected, who had been examined for sputum, urine, blood, pleural effusion, ascites, cerebrospinal fluid and wound secretions and other body fluid samples. And the results showed that Klebsiella pneumoniae was positive, including demographic data, underlying disease status, drug sensitivity test, infection-related indicators, life support, prognostic indicators.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 546
• Est. completion date: February 28, 2020
• Est. primary completion date: July 31, 2019
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adult whose body fluid were sampled during ICU stay and Klebsiella pneumoniae was detected, followed by drug sensitivity test (including reporting the test results after the patient was transferred out of ICU or died).

Exclusion Criteria:

• Age were less than 18 years old;

• Patients stayed in ICU was less than 48 hours.

Related Conditions & MeSH terms

• Drug Resistance
• Pneumonia

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Fujian Provincial Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	prognostic indicators	30-day survival rate	30 day
Primary	ICU stays	the length that patients stay in ICU	about a mouth