A Pilot Study of the Bioavailability of Nasal Naloxone

Status Completed

Clinical Trial Summary

The overall is aim of this pilot study is to give a preliminary estimation of key parameters of the pharmacokinetics of a proper formulation of intranasal naloxone. These data will be used to design a well justified protocol for the final estimation of these parameters: - Preliminary estimation of bioavailability of this intranasal naloxone in human, healthy volunteers - Preliminary estimation of the maximum serum concentration (Cmax) of this formulation - Preliminary estimation of the time to maximum serum concentration (Tmax) of this formulation - Safety of the formulation

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Drug Overdose

Clinical Trial Details

NCT number	NCT01939444
Study type	Interventional
Source	Norwegian University of Science and Technology
Contact
Status	Completed
Phase	Phase 2
Start date	August 2013
Completion date	November 2014

View Details

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