Ultrasound Method to Measure Fibrosis of the Liver in Children

Status Recruiting

Clinical Trial Summary

HYPOTHESIS: The investigators hypothesize that sonoelastography (SE) provide accurate quantitative measurements that can be used to stage liver fibrosis in pediatric patients with chronic liver disease.

Specific Aims:

1. To measure liver stiffness with sonoelastography in adults with suspect diffuse liver disease who will undergo nonfocal liver biopsy as part of their routine clinical care.

2. To assess the sensitivity and specificity of sonoelastography for the detection and staging of liver fibrosis.

3. To obtain sonoelastography values of the liver in healthy children (control subjects).

Clinical Trial Description

n/a

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02086708
Study type	Interventional
Source	Massachusetts General Hospital
Contact	Uzma Shah, MD, FAAP
Phone	617-726-0319
Email	USHAH@partners.org
Status	Recruiting
Phase	N/A
Start date	June 2010
Completion date	March 2015

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