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Drug-Induced Anaphylaxis clinical trials

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NCT ID: NCT06406114 Not yet recruiting - Clinical trials for Drug Hypersensitivity

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

DACAT
Start date: August 1, 2024
Phase: Phase 2
Study type: Interventional

Cephalosporin antibiotics are commonly used but can result in allergic reactions and anaphylaxis. There is no clear diagnostic approach for cephalosporin-allergic patients, and guidance for the use of other antibiotics in allergic patients is based on side chain chemical similarity and limited skin testing evidence. This project includes a clinical trial and mechanistic studies to optimize the approach to cephalosporin allergy and advance future diagnostics.