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Efficacy and Safety of Hetrombopag in Non-severe Aplastic Anemia

Aplastic Anemia Clinical Trial

Official title:
Efficacy and Safety of Hetrombopag in Non-severe Aplastic Anemia: a Prospective Single Arm Study

Clinical Trial Summary

This is a prospective one arm study to explore the efficacy and safety of Hetrombopag in non-severe aplastic anemia. Patients meeting the inclusion and exclusion criteria would be recruited. Treatment of Hetrombopag would be started with 5mg/day. The dosage would be increased by 2.5mg/day every 2 weeks if the platelet count remains less than 20×10e9/L and reduced if the platelet count reaches over than 150×10e9/L. The maximum dosage is 15mg/day. All patients would receive treatment for at least 6 months except that the platelet <20×10e9/L at the dosage of 15mg/day for 4 weeks or the platelet ≥200×10e9/L at the dosage of 5mg/week for 2 weeks. The hematological response rate and safety will be recorded and compared at D15, 1month, 1.5month, 2month, 3month, 4month, 5month, 6month, 8month, 10month and 1year.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05018936
Study type Interventional
Source Peking Union Medical College Hospital
Contact Bing Han, Docter
Phone +8613601059938
Email hanbing_li@sina.com
Status Not yet recruiting
Phase Phase 2/Phase 3
Start date October 1, 2021
Completion date December 1, 2023
View Details
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