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Evaluation of Smoked THC and CBD in Men and Women — S-TACOFS  

Drug Abuse Clinical Trial

Official title:
Evaluation of Smoked THC and CBD in Oral Fluid, Pharmacokinetics, and Subjective and Neurocognitive Effects in Men and Women

Clinical Trial Summary

The purpose of this study is to determine the pharmacokinetics and pharmacodynamics of inhaled cannabis with varying amounts of delta-9-tetrahydrocannabinol (THC), and cannabidiol (CBD) and to evaluate detection of recently smoked THC in oral fluid.

Clinical Trial Description

This double-blind placebo controlled, within-subject study study will assess testing devices that can measure biochemical markers in oral fluid and neurocognitive-performance markers of recent cannabis use. Other pharmacodynamic effects of inhaled cannabis with CBD and THC will be determined and the pharmacokinetics of THC, CBD, and respective metabolites will be assessed in whole blood. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05037487
Study type Interventional
Source University of California, Los Angeles
Contact Ziva Cooper, PhD
Phone 310-206-9942
Email zcooper@mednet.ucla.edu
Status Recruiting
Phase Phase 1
Start date September 1, 2022
Completion date June 2024
View Details
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