View clinical trials related to Double Outlet Right Ventricle.
Filter by:This clinical trial is studying the use of different levels of oxygen exposure during and after cardiopulmonary bypass in eligible infants to learn about its safety during heart surgery. In addition to having the various doses of oxygen, participants will also have blood samples, ultrasounds of the head, and brain wave patterns monitored. The hypotheses of this trial are: - that there will be no difference with regards to adverse events between the infants in the normoxia group compared to the infants in the standard of care group - there will be a significant difference in the measured partial pressure of oxygen (PaO2) values between the two treatment groups. - the use of normoxia during cardiopulmonary bypass and in the immediate post-operative period will result in clinically significant decrease in oxidative stress as measured by thiobarbituric acid reactive substances (TBARS) after cardiac surgery
The purpose of this study is to investigate the security and validity of transesophageal echocardiography(TEE)-guided perventricular device closure(TPDC) through minithoracotomy in treatment of infundibular ventricular septal defect(IVSD) with asymmetric occluder.
The purpose of this study is to utilize cardiac imaging data acquired as part of the standard of care for these patients, such as MRI, 3D echo, and CT, and existing 3D reconstruction protocols to assess the feasibility of using surgical planning in the treatment of patients with complex cardiac defects. The specific aims of the project are as follows: 1. Develop a protocol to reconstruct heart models from patient imaging data and perform "virtual" surgery on reconstructed 3D anatomy using appropriate, pre-existing patient datasets. 2. Use the developed protocol to prospectively plan and evaluate the possible surgical options for new patients. 3. Validate that the optimal virtual anatomy agrees with what was surgically implemented using post-operative patient scans, when available.
This study will investigate Ebstein's anomaly, a congenital abnormality of the tricuspid valve of the heart and try to identify the genetic origins of the disease. Adults and children 2 years of age and older with Ebstein's anomaly and healthy volunteers may be eligible for this study. Participants undergo the following procedures: - Blood tests: Three tube of blood will be collected, with the total amount limited to about half a teaspon for each two pounds of body weight. - Saliva sample collection: A small amount of saliva is collected by spitting into a sterile container. - Oral (cheek) swab: Cells are collected from the mouth using a soft brush to swab the inside lining of the cheek. - Electrocardiogram: The electrical activity of the heart is recorded using electrodes placed on the chest. - Echocardiogram: Heart function is assessed using ultrasound.