DNA Damage Clinical Trial
Official title:
A Non-invasive Method to Assess DNA Damage in Individual Sperm
The purpose of this study is to find a non-invasive way to discover DNA (deoxyribonucleic acid, which is the genetic material inside your cells) alterations in the sperm's head, in the near future leading us to choose the "good sperm" in a simplified manner. This could then increase chances of a successful in-vitro fertilization (IVF) treatment when there are sperm abnormalities.
If you take part in this study,
1. Your physician is asking you to provide a semen sample as you already would. The sample
will be taken to the IVF lab which would occur if you were not involved in this
research. The part that would be thrown away is then further analyzed under a polarized
light microscope. The sample is exposed to ultraviolet (UV) light for a period of 20
minutes after which it is analyzed under the microscope again, looking for any changes
when compared the sample that was not exposed to UV light. The sample is then
discarded.
2. Your name will be removed from the sample after the regular semen analysis is done;
therefore there will be no way of associating the research results with you. No
information will be needed from you and you will not be contacted in the future
regarding this research.
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Observational Model: Cohort, Time Perspective: Prospective
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