Prior Abdominal Surgery: A Potential Risk Factor for Colonic Diverticulosis or Diverticulitis

Diverticulitis Clinical Trial

Official title:

Prior Abdominal Surgery: A Potential Risk Factor for Colonic Diverticulosis or Diverticulitis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05384925
• Other study ID #: 0107-20
• Status: Completed
• Start date: April 12, 2020
• Est. completion date: April 1, 2022

Study information

• Verified date: May 2022
• Source: Assaf-Harofeh Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Background & Aims:

Abnormal colonic pressure profiles have been associated with an increased risk of colonic diverticulosis. A surgical history is a known risk factor for abdominal adhesions, and these may lead to increased intraluminal colonic pressure. We assessed whether previous abdominal surgery is associated with colonic diverticulosis or diverticulitis.

Methods:

The investigators analyzed data from a prospective study of patients undergoing colonoscopy for different indications from 2020 through 2021. Patients completed a structured questionnaire concerning previous abdominal surgeries, dietary and lifestyle exposures including smoking and alcohol use, and co-morbidities.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 359
• Est. completion date: April 1, 2022
• Est. primary completion date: May 22, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• patients > 18 years old who are going through colonoscopy in shamir medical center for any reason

Exclusion Criteria:

• inadequate preparation (Boston Bowel Preparation Quality Scale <6);

• previous colonic resection based on history and colonoscopy;

• previous colon cancer.

Related Conditions & MeSH terms

• Diverticulitis
• Diverticulosis, Colonic
• Diverticulum

Intervention

Other:
• comparison
abdominal surgery as a risk factor for diverticulosis

Locations

Country	Name	City	State
Israel	Asag Harofeh Medical Center	Be'er Ya'aqov

Sponsors (1)

Lead Sponsor	Collaborator
Assaf-Harofeh Medical Center

Country where clinical trial is conducted

Israel, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	correlation between prior abdominal surgery and the development of diverticulosis	the investigators are willing to see if prior abdominal surgery raise the patient's risk of developing future diverticulosis. The investigators use questionere to collect data from patients. The final measurements will be calculatrd with spss software	in the end of the study (estimated in 1 year)