Diverticulitis Clinical Trial
Official title:
Prospective Randomized Clinical Trial Assessing the Efficacy of a Short Course of Intravenous Amoxicillin Plus Clavulanic Acid Followed by Oral Antibiotic in Patients With Uncomplicated Acute Diverticulitis
Medical treatment of uncomplicated acute diverticulitis is not standardized and there is an enormous diversity in clinical practice. The investigators' aim was to demonstrate that uncomplicated diverticulitis can be managed with oral amoxicillin plus clavulanic acid with a short hospital admission.
A prospective randomized trial was established to compare patients with uncomplicated diverticulitis who received oral antibiotic after a short course of intravenous antibiotic, with those who received intravenous antibiotic for a longer period. We included 50 patients, 25 in each group. Patients in group 1 begun oral antibiotic as soon as they improved and were discharged the day after. Patients in group 2 received intravenous antibiotic for 7 days. Both groups received oral antibiotic at discharge. The endpoint of the study was "failure of treatment" which was defined as the impossibility of discharging on the expected day, emergency admission or hospital readmission. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT03042091 -
Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery
|
Early Phase 1 | |
| Completed |
NCT02246361 -
Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication
|
Phase 4 | |
| Completed |
NCT01476995 -
Prognostic Indicators as Provided by the EPIC ClearView
|
N/A | |
| Completed |
NCT01081054 -
Hospitalization or Ambulatory Treatment of Acute Diverticulitis
|
Phase 4 | |
| Completed |
NCT00195351 -
Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection
|
Phase 4 | |
| Completed |
NCT03337984 -
Damage Control Surgery in the Treatment of Complicated Diverticulitis
|
||
| Recruiting |
NCT06210724 -
FIT in Diverticulitis
|
||
| Completed |
NCT01986686 -
Recurrence Following Nonoperative Management of 1st Episode of Hinchey II Diverticulitis
|
N/A | |
| Completed |
NCT01477190 -
Spinal Analgesia for Colonic Resection Using an Enhanced Recovery After Surgery (ERAS) Program
|
Phase 1/Phase 2 | |
| Completed |
NCT01056913 -
NITI CAR27 (ColonRing) Compression Anastomosis in Colorectal Surgery
|
Phase 4 | |
| Completed |
NCT00230971 -
Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI)
|
Phase 4 | |
| Completed |
NCT00468455 -
Post-Op Quality of Life After Colorectal Surgery
|
N/A | |
| Enrolling by invitation |
NCT03700593 -
Feasibility and Safety of Single Port Robot in Colorectal Procedures
|
||
| Recruiting |
NCT04095663 -
Comparison of Surgery and Medicine on the Impact of Diverticulitis (COSMID) Trial
|
N/A | |
| Completed |
NCT00545740 -
Prevention of Recurrence of Diverticulitis
|
Phase 3 | |
| Recruiting |
NCT01837342 -
Multicenter Study Comparing Morbidity and Quality of Life Associated in the Treatment by Surgical Resection and the Conservative Treatment, After Favorable Evolution of Purulent Peritonitis That Originates From Diverticulitis Treated by Mini-invasive Surgery
|
N/A | |
| Completed |
NCT01727388 -
Informativeness to Digital Rectal Examination
|
Phase 3 | |
| Completed |
NCT00554099 -
Asacol Acute Diverticulitis(DIVA)Study
|
Phase 2 | |
| Completed |
NCT04173182 -
Confocal Laser Endomicrospy in Colonic Diverticular Disease
|
||
| Completed |
NCT02200055 -
Using Electrical Bioimpedance Assessments to Estimate Perioperative Total Body Water and Postoperative Fluid Need
|
N/A |