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NCT ID: NCT05939193 Recruiting - Acute Kidney Injury Clinical Trials

Effect of Urine-guided Hydration on Acute Kidney Injury After CRS-HIPEC

Start date: July 24, 2023
Phase: N/A
Study type: Interventional

Acute renal injury (AKI) is a common complication after cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC), and is associated with worse outcomes. Available evidences show that maintaining intraoperative urine output ≥ 200 ml/h by fluid and furosemide administration may reduce the incidence of AKI in patients undergoing cardiopulmonary bypass. The investigators hypothesize that, for patients undergoing CRS-HIPEC, intraoperative urine-volume guided hydration may also reduce the incidence of postoperative AKI.