Cognitive Behavioural Therapy in Dissociative Seizures

Dissociative Seizures Clinical Trial

Official title: Cognitive Behavioural Therapy in Dissociative Seizures: A Randomised Controlled Trial

Status Active, not recruiting

Clinical Trial Summary

The purpose of this study is to determine whether adults with disoociative (psychogenic non-epileptic) seizures receiving cognitive behavioural therapy (CBT) show a greater reduction in seizures and health service use and greater improvement in employment status and overall psychosocial functioning than patients who receive standard care.

Clinical Trial Description

Preliminary results from a pilot study demonstrated that cognitive behavioural therapy (CBT) is associated with a significant benefit for patients with dissociative seizures. The current study aims to extend these findings by conducting a randomised controlled trial comparing CBT with standard outpatient medical care. Standard outpatient care has been chosen as the comparison treatment as it most closely resembles what is currently offered to this group of patients by the National Health Service. The primary outcome measure will be seizure frequency. Secondary outcome measures will be work and social adjustment and health service use.

Our hypothesis is that CBT will be superior to standard outpatient care for patients with dissociative seizures as determined by the above measures. ;

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Conversion Disorder
• Dissociative Disorders
• Dissociative Seizures
• Seizures

• NCT number: NCT00688727
• Study type: Interventional
• Source: South London and Maudsley NHS Foundation Trust
• Status: Active, not recruiting
• Phase: N/A
• Start date: March 2001
• Completion date: February 2009