Personal Music for Disorders of Consciousness

Status Recruiting

Clinical Trial Summary

Background: The evaluation and treatment of disorders of consciousness(DOC) is a challenging undertaking. Now many neuroimaging techniques were used to detect the level of consciousness and electroencephagram(EEG) was widely used because of its high temporal resolution. Music would be an effective for DOC, due to its highly arousal value. Preferred music was near to persons, so that it would excite more range of cortical and increase the functional connectivity between cortices. Methods: The exploratory study included 15 health controls and 30 DOC, with 15 minimally conscious state(MCS) and 15 vegetative state(VS). After 5 minutes baseline silence, they listened to relaxing music(RM), preferred music(PM) and amplitude modulated sound(AMS), with 5 minutes baseline silence in the end, meanwhile EEG recorded their cortical activity. Each music was appropriately 5 minutes and separated by 3 minutes washout. Discussion: The study would verify the effect of preferred music to the functional connectivity of DOC. Music would excite the networks related to consciousness by cross-modal.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05382260
Study type	Interventional
Source	Zhujiang Hospital
Contact	Qiuyi M Xiao, BSc
Phone	+8618302083474
Email	2936404912@qq.com
Status	Recruiting
Phase	N/A
Start date	May 26, 2022
Completion date	December 31, 2023

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT05954650` - Clinical Validity of the Minimally Conscious State "Plus" and "Minus"
Suspended	`NCT04244058` - Changes in Glutamatergic Neurotransmission of Severe TBI Patients	Early Phase 1
Not yet recruiting	`NCT05833568` - Five-day 20-minute 10-Hz tACS in Patients With a Disorder of Consciousness	N/A
Recruiting	`NCT05219331` - Hydrocephalus Treatment on Persistent Disorder of Consciousness	N/A
Recruiting	`NCT05706831` - Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases	N/A
Completed	`NCT03114397` - Long-term Effect of tDCS in Patients With Disorders of Consciousness	N/A
Active, not recruiting	`NCT03623828` - Treating Severe Brain-injured Patients With Apomorphine	Phase 2
Active, not recruiting	`NCT05734183` - Multisensorial IMmersive Experiences (MIME) in Disorders of Consciousness	N/A
Recruiting	`NCT05714215` - SECONDs' Italian Translation and Transcultural Validation
Completed	`NCT04035655` - Sub-study of the NEURODOC Project : Neurophysiological Evaluation of a Routine Care Open Label tDCS Session	N/A
Active, not recruiting	`NCT05747170` - Olfactory Stimulation in Severe Brain Injury	N/A
Active, not recruiting	`NCT03826407` - Development of a Point of Care System for Automated Coma Prognosis
Recruiting	`NCT03576248` - CONsciousness Transcranial Electric STimulation	N/A
Recruiting	`NCT03611166` - Proteomics for Chronic Disorder of Consciousness
Not yet recruiting	`NCT05820178` - tDCS and rTMS in Patients With Early Disorders of Consciousness	N/A
Recruiting	`NCT05343507` - Ketamine to Treat Patients With Post-comatose Disorders of Consciousness	Phase 2/Phase 3
Completed	`NCT05536921` - Eye Tracking Technology in the Diagnosis of Neurological Patients
Recruiting	`NCT05740735` - Emotional and Neutral Sounds for Neurophysiological Prognostic Assessment of Critically Ill Patients With a Disorder of Consciousness
Completed	`NCT02647996` - Functional Connectivity Measurement After Severe Traumatic Brain Injury
Completed	`NCT04530968` - Metabolic Abnormalities and Intestinal Microecology in Patients With Chronic Disorders of Consciousness