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Light Therapy in Disorders of Consciousness: Behavioral, Neuroimaging and (Neuro)Physiological Assessments.

Disorder of Consciousness Clinical Trial

Official title:
Luminothérapie Chez Les Patients présentant un état de la Conscience altérée: évaluations Comportementale, de Neuroimagerie et (Neuro)Physiologique.

Clinical Trial Summary

In this randomized, double-blind, placebo controlled project, the investigators would like to assess the effect of a specific light, as compared to placebo light, on wakefulness (circadian rhythms, homeostasy, sleep-wake cycle), awareness (perceptual and self consciousness), cognition (attention, memory) and underlying brain activity (electrophysiology and neuroimaging)

Clinical Trial Description

The investigators will use behavioral (CRS-R, CAP, actimeter, brainstem reflexes), physiological (body core temperature, saliva, urine, heart rate, blood sample), neuroimaging and neurophysiological tools (PET, fMRI, TMS-EEG, resting-state and auditory paradigm EEG) before, during and after treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03174119
Study type Interventional
Source University Hospital of Liege
Contact Séverine Blandiaux, 1
Phone +3243663915
Email severine.blandiaux@ulg.ac.be
Status Not yet recruiting
Phase N/A
Start date February 2019
Completion date January 2021
View Details
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