Clinical Trials Logo
  1. Home
  2. Disorder of Consciousness
  3. NCT03174119

Light Therapy in Disorders of Consciousness: Behavioral, Neuroimaging and (Neuro)Physiological Assessments.

Disorder of Consciousness Clinical Trial

Official title:
Luminothérapie Chez Les Patients présentant un état de la Conscience altérée: évaluations Comportementale, de Neuroimagerie et (Neuro)Physiologique.

Clinical Trial Summary

In this randomized, double-blind, placebo controlled project, the investigators would like to assess the effect of a specific light, as compared to placebo light, on wakefulness (circadian rhythms, homeostasy, sleep-wake cycle), awareness (perceptual and self consciousness), cognition (attention, memory) and underlying brain activity (electrophysiology and neuroimaging)

Clinical Trial Description

The investigators will use behavioral (CRS-R, CAP, actimeter, brainstem reflexes), physiological (body core temperature, saliva, urine, heart rate, blood sample), neuroimaging and neurophysiological tools (PET, fMRI, TMS-EEG, resting-state and auditory paradigm EEG) before, during and after treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03174119
Study type Interventional
Source University Hospital of Liege
Contact Séverine Blandiaux, 1
Phone +3243663915
Email severine.blandiaux@ulg.ac.be
Status Not yet recruiting
Phase N/A
Start date February 2019
Completion date January 2021
View Details
See also
  Status Clinical Trial Phase
Completed NCT05954650 - Clinical Validity of the Minimally Conscious State "Plus" and "Minus"
Suspended NCT04244058 - Changes in Glutamatergic Neurotransmission of Severe TBI Patients Early Phase 1
Not yet recruiting NCT05833568 - Five-day 20-minute 10-Hz tACS in Patients With a Disorder of Consciousness N/A
Recruiting NCT05219331 - Hydrocephalus Treatment on Persistent Disorder of Consciousness N/A
Recruiting NCT05706831 - Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases N/A
Completed NCT03114397 - Long-term Effect of tDCS in Patients With Disorders of Consciousness N/A
Active, not recruiting NCT03623828 - Treating Severe Brain-injured Patients With Apomorphine Phase 2
Active, not recruiting NCT05734183 - Multisensorial IMmersive Experiences (MIME) in Disorders of Consciousness N/A
Recruiting NCT05714215 - SECONDs' Italian Translation and Transcultural Validation
Completed NCT04035655 - Sub-study of the NEURODOC Project : Neurophysiological Evaluation of a Routine Care Open Label tDCS Session N/A
Active, not recruiting NCT05747170 - Olfactory Stimulation in Severe Brain Injury N/A
Active, not recruiting NCT03826407 - Development of a Point of Care System for Automated Coma Prognosis
Recruiting NCT03576248 - CONsciousness Transcranial Electric STimulation N/A
Recruiting NCT03611166 - Proteomics for Chronic Disorder of Consciousness
Recruiting NCT05382260 - Personal Music for Disorders of Consciousness N/A
Not yet recruiting NCT05820178 - tDCS and rTMS in Patients With Early Disorders of Consciousness N/A
Recruiting NCT05343507 - Ketamine to Treat Patients With Post-comatose Disorders of Consciousness Phase 2/Phase 3
Completed NCT05536921 - Eye Tracking Technology in the Diagnosis of Neurological Patients
Recruiting NCT05740735 - Emotional and Neutral Sounds for Neurophysiological Prognostic Assessment of Critically Ill Patients With a Disorder of Consciousness
Completed NCT02647996 - Functional Connectivity Measurement After Severe Traumatic Brain Injury