Study of Ruxolitinib Cream for the Treatment of Discoid Lupus

Updated 04/30/2024

Status Completed

Clinical Trial Summary

The purpose of this study is to assess the potential efficacy of topical ruxolitinib for the treatment of discoid lupus erythematosus (DLE)

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04908280
Study type	Interventional
Source	University of Rochester
Contact
Status	Completed
Phase	Phase 2
Start date	May 4, 2022
Completion date	March 4, 2024

See also
	Status	Clinical Trial	Phase
	Withdrawn	`NCT03866317` - A Study to Assess the Safety and Efficacy of Secukinumab in Alleviating Symptoms of Discoid Lupus Erythematosus	Phase 2
	Completed	`NCT00001680` - A Pilot Trial of Topical Thalidomide for the Management of Chronic Discoid Lupus Erythematosus	Phase 2
	Recruiting	`NCT05591222` - Study of Daxdilimab (HZN-7734) in Patients With Moderate-to-Severe Primary Discoid Lupus Erythematosus	Phase 2
	Completed	`NCT00625521` - Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions	Phase 2
	Completed	`NCT02125695` - Pilot Tape Harvesting Study	N/A
	Completed	`NCT05362188` - Topical Nicotinamide in Treatment of DLE	Early Phase 1
	Completed	`NCT00708916` - Safety Study of Clinical and Immune Effects of Phosphodiesterase 4 (PDE-4) Inhibitor in Cutaneous Lupus Patients	Phase 1/Phase 2
	Terminated	`NCT03958955` - Efficacy and Safety of Delgocitinib Cream in Discoid Lupus Erythematosus.	Phase 2
	Terminated	`NCT03159936` - Oral Tofacitinib in Adult Subjects With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE)	Early Phase 1
	Completed	`NCT00691769` - Expression of Fas Protein in Skin Biopsies of Participants With Scarring Alopecia
	Completed	`NCT00608673` - Comparing the Therapeutic Efficacy of Pimecrolimus Cream With Betamethasone Cream for Discoid Lupus Erythematosus	N/A
	Recruiting	`NCT06261021` - Study to Evaluate the Efficacy of Ruxolitinib 1.5% Cream in Adult Subjects With Discoid Lupus Erythematosus	Phase 2
	Completed	`NCT00625157` - Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions (2)	Phase 2