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Disc Degeneration clinical trials

View clinical trials related to Disc Degeneration.

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NCT ID: NCT06367855 Not yet recruiting - Surgery Clinical Trials

Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF : Double Blinded, Randomized Control Trial

MIS-TLIF
Start date: May 1, 2024
Phase: Phase 4
Study type: Interventional

Researchers are considering Dexamethasone as preemptive medication before minimally invasive spine fusion surgery to minimize postoperative back pain with minimal side effects, aiming to enhance the effectiveness of surgery and improve patient outcomes.

NCT ID: NCT06025175 Not yet recruiting - Disc Degeneration Clinical Trials

Low Level Lazer Therapy Effect on Vertebral Artery Blood Flow in Elderly With Cervical Disc Degeneration

Start date: September 15, 2023
Phase: N/A
Study type: Interventional

This study will include 60 elderly patients with cervical disc degeneration, from both gender who are aged from 60 - 75 years old.

NCT ID: NCT05971329 Not yet recruiting - Disc Degeneration Clinical Trials

Pilot Study of ZetaFuseā„¢ Bone Graft for the Treatment of Cervical Degenerative Disc Disease

Start date: September 2024
Phase: Early Phase 1
Study type: Interventional

The goal of this pilot clinical trial is to test the safety and preliminary performance of the ZetaFuse Bone Graft in patient requiring fusion of the C3-C7 vertebral bones due to pain or loss of neurological function. Participants will be treated with ZetaFuse during surgical intervention to reduce pain and the loss of neurological function.

NCT ID: NCT05745129 Enrolling by invitation - Low Back Pain Clinical Trials

Applying Artificial Intelligence in Developing Personalized and Sustainable Healthcare for Spinal Disorders

AID-Spine
Start date: December 1, 2021
Phase:
Study type: Observational

The primary objective is to use machine learning methods on large survey and health register data to identify participants with different treatment trajectories and health outcomes after surgical and/or conservative treatment for spinal disorders. Secondary objectives are to 1) conduct external validation of the prediction models, and 2) explore how the prediction models can be implemented into AI-based clinical co-decision tools and interventions.

NCT ID: NCT05641857 Completed - Disc Degeneration Clinical Trials

Lumbar Spine on MRI and Low Back Pain in Elite Cross-country Skiers

Start date: September 1, 2022
Phase:
Study type: Observational

The investigators will examine the prevalence of low-back pain and disc degeneration among Finnish elite skiers between 16 and 35 years of age and compare these findings with the data collected among healthy volunteers studied between 1994-2021.

NCT ID: NCT05412277 Active, not recruiting - Low Back Pain Clinical Trials

VIA Disc Nucleus Pulposus Older Patients Pilot

Start date: October 17, 2022
Phase: N/A
Study type: Interventional

VIA Disc NP is a non-surgical intervention intended to supplement the nucleus pulposus tissue in degenerated intervertebral discs.

NCT ID: NCT05315375 Completed - Disc Degeneration Clinical Trials

Post-trauma Lumbar Vertebral Body Reconstruction Using Expandable Cages

Start date: January 2, 2010
Phase:
Study type: Observational

INTRODUCTION The expandable cage technology is not new, but several questions remain under-studied. Among them, there are the sagittal balance, the subsidence and the adjacent disc degeneration. Moreover, assessment of the correction and kyphosis regardless of the physiological angles can possibly lead to calculation bias. The objective of this study was to assess the extent to which the functional outcomes were correlated to the quality of the reduction, within a homogeneous series of lumbar vertebral body reconstruction with expandable cages for trauma. MATERIAL AND METHODS Twenty-seven patients with a mean follow-up of 3.9 years were retrospectively analyzed. The Oswestry Disability Index (ODI) was the main outcome and its association with other variables was sought. The local kyphosis and the regional traumatic angle using Stagnara's physiological angles were measured. The lumbar lordosis (LL) was compared to the Pelvic Incidence (PI). The subsidence of the cage and the adjacent disc degeneration (using the UCLA grading score) were quantified. Bone quality was assessed through the Hounsfield Unit of the vertebral body.

NCT ID: NCT05201287 Active, not recruiting - Low Back Pain Clinical Trials

VIA Disc NP Pilot for Patients With Symptomatic Degenerated Discs

Start date: December 30, 2021
Phase: N/A
Study type: Interventional

VIA Disc NP is an allograft intended to supplement the nucleus pulposus tissue in degenerated intervertebral discs.

NCT ID: NCT05059249 Completed - Low Back Pain Clinical Trials

Effects of Mechanical Versus Manual Traction in the Management of Low Back Pain.

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

This study compared the effects of mechanical and manual traction on pain, disability and lumbar spinal curvature in patients with discogenic low back pain

NCT ID: NCT04712487 Completed - Disc Degeneration Clinical Trials

Low-grade Infections of the Intervertebral Discs

Start date: December 1, 2018
Phase:
Study type: Observational

The purpose of this prospective, observational study was to evaluate frequency and characteristics of low-grade infections of the intervertebral discs in an unselected real-life patient population undergoing surgery for degenerative pathologies of the spine.