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Clinical Trial Summary

This study is investigating the optimal dose and the advantage in combining investigational immunotherapy drugs known as Retifanlimab, INCAGN02385 and INCAGN02390 to improve the responses to CAR T-cell therapy. Additionally, the study will investigate that triple checkpoint blockade of PD-1, TIM-3 and LAG-3 molecules will overcome CAR T-cell therapy resistance in patients with suboptimal responses.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06290622
Study type Interventional
Source University of Alabama at Birmingham
Contact Mayur Narkhede, MD
Phone (205) 934-2248
Email msnarkhede@uabmc.edu
Status Not yet recruiting
Phase Phase 1
Start date June 30, 2024
Completion date January 31, 2028

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