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Differential Diagnosis clinical trials

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NCT ID: NCT04478045 Completed - Emergencies Clinical Trials

The Application of Point-of-care Ultrasonography in Differential Diagnosis of Shock in Emergency and Critical Care

Start date: August 1, 2020
Phase:
Study type: Observational

For the emergency physicians and critical care specialists, how to quickly recognize shock from diverse clinical features and immediately treat shock patients to prevent progression to irreversible organ dysfunction from initially reversible shock condition are important issues and challenges. In recent years, ultrasonography had been extensively used in clinical practice recently, and well-trained medical staffs can quickly and easily apply ultrasound to evaluate, examine, diagnose, and even treat the patients. The clinical application of point-of-care ultrasound can help the first-line physicians rapidly evaluate and diagnose the main symptoms and signs of the patients at bedside, and further initially stabilize and appropriately treat the patients subsequently. The aim of this program is to prospectively collection of the findings of point-of-care ultrasonography in shock patients at emergency room in NTUH. The clinical manifestations, and followed up the examinations, treatments, and prognosis will also be collected. The effect of bedside ultrasound on differential diagnosis and treatment of shock patients will be analyzed. The results of the current study can provide the base for further clinical trials and set up of shock team.

NCT ID: NCT04334720 Recruiting - Clinical trials for Differential Diagnosis

PET/MRI Study on Changes of Fat and Muscle Metabolism.

Start date: July 1, 2019
Phase:
Study type: Observational

False positives for Brown Fat & Muscle(F&M) always affect the evaluation of metabolic disease treatment. Recently, using PET/CT,international journals such as Journal of Nuclear Medicine reported that the amount of active brown fat was correlated with renal creatinine clearance and subject to regulation by atrial natriuretic peptide in addition to association of season and temperature. At present,studies based on PET/CT have shown that elimination of the above factors, brown fat(even muscle) will still appear false positive metabolism in tumor patients. In view of the basis of Positron emission computed tomography/Magnetic resonance (PET/MRI) brain function research,our team speculate that it may be related to psychological or cortex metabolism. And there is a lack of studies on the correlation between the psychosocial,cortex structure and metabolism. Therefore, it suggests that,combination of structure and metabolism,PET/MRI will play a role in studying the effects of psychological on F&M false-positive metabolism in malignant patients. In this project, the investigators intend to observe the changes of F&M metabolism with psychological and cortex metabolism after comprehensive treatment in malignant patient by combining PET/MRI. The relationship between F&M metabolism and psychological will be deeply analyzed to provide scientific basis for the development of the differential diagnosis and assessment.