Effects of Calcium and Phytate on Zinc Absorption

Dietary Zinc Absorption Clinical Trial

Official title:

Effects of Calcium and Phytate on Zinc Absorption

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00754390
• Other study ID #: GFHNRC042
• Status: Completed
• Phase: N/A
• Start date: November 2005
• Est. completion date: May 2006

Study information

• Verified date: May 2018
• Source: USDA Grand Forks Human Nutrition Research Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study is determine the effects of dietary calcium and phytate on zinc absorption.

Description:

Zinc absorption is tested from 2 days of consuming each of four diets with zinc-65 isotope, followed by retention monitoring in a whole body scintillation counter for 4 weeks. All four 4 experimental diets are tested with each subject, in randomized order, for a total of 16 weeks.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 17
• Est. completion date: May 2006
• Est. primary completion date: May 2006
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 21 Years to 50 Years

Eligibility

Inclusion Criteria:

• Average weight for height

Exclusion Criteria:

• Medications other than birth control pills or hormone replacement therapy,

• Pregnancy within last 6 months

Related Conditions & MeSH terms

• Dietary Zinc Absorption

Intervention

Dietary Supplement:
• Moderate Calcium, Low phytate Diet
Participants consumed diet containing 700 milligrams calcium and 440 milligrams of phytate for 4 weeks
• Moderate Calcium, High Phytate Diet
Participants consumed diet containing 700 milligrams calcium and 1800 milligrams of phytate for 4 weeks
• High Calcium, Low Phytate Diet
Participants consumed diet containing 1900 milligrams calcium and 440 milligrams of phytate for 4 weeks
• High Calcium, High Phytate Diet
Participants consumed diet containing 1900 milligrams calcium and 1800 milligrams of phytate for 4 weeks

Locations

Country	Name	City	State
United States	United States Department of Agriculture Grand Forks Human Nutrition Research Center	Grand Forks	North Dakota

Sponsors (1)

Lead Sponsor	Collaborator
USDA Grand Forks Human Nutrition Research Center

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Zinc Absorption	Retention of Zinc-65 was monitored for 28 days by whole body scintillation counting. The percentage of Zinc-65 absorbed was estimated from the y-intercept of the linear portion of a semilogarithmic retention plot of percent Zinc-65 retained versus time	16 weeks