Effect of Carbohydrate-protein Co-ingestion on Short-term Recovery

Dietary Supplementations Clinical Trial

Official title:

Effects of Post-Exercise Recovery Drink Composition on Subsequent Performance in Masters Class Athletes

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04859491
• Other study ID #: MCAs and Short-Term Recovery
• Status: Completed
• Phase: N/A
• Start date: July 22, 2021
• Est. completion date: December 5, 2021

Study information

• Verified date: May 2022
• Source: University of Central Florida
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to determine whether the consumption of a carbohydrate, carbohydrate plus protein, or placebo sports drink during a 2-hour recovery period effectively moderates performance decrements during a subsequent bout of high-intensity exercise. This information will benefit any endurance-trained masters class athlete who may need to compete or train multiple times a day.

Description:

To test the hypothesis, this study will utilize a randomized, double-blind, placebo-controlled between-subject design to examine the effects of carbohydrate (CHO) and carbohydrate-protein (CHO-P) supplementation on short-term recovery following aerobic interval exercise (INT) and time to exhaustion (TTE) testing in maters class athletes. After completing the informed consent and screening process (Visit #1), each participant will be assessed for their anthropometric measures as well as body composition and will complete a graded exercise test to volitional exhaustion on a cycle ergometer to determine VO2peak. Forty-eight to 72 hours after Visit #1, or VO2peak testing, participants will return to the lab for familiarization with the INT exercise protocol and TTE test (Visit #2). Within forty-eight to 72 hours after familiarization (Visit #2), participants will return to the lab for Visit #3 to complete INT exercise and TTE, a 2-hour passive recovery period including the consumption of one of three treatments (CHO, CHO-P, PLA), followed by repeated INT exercise and TTE, heart rate variability and sweat rate determination. Participants will also complete the Nutritional Recovery Practices, Knowledge, and Beliefs of Australian Triathletes survey during the 2-hour recovery period. Participants will be asked to complete the ASA24®, an automated self-administered 24-hour dietary assessment tool during the 5-9-day period between familiarization (Visit #2) and the experimental protocol (Visit #3).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 24
• Est. completion date: December 5, 2021
• Est. primary completion date: December 5, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 35 Years to 59 Years

Eligibility

Inclusion Criteria:

• Men between the ages of 35 and 59 years

• Free of any physical limitations as determined by the Exercise Preparticipation Health Screening Questionnaire for Exercise Professionals (PHSQEP), and a Physical Activity Readiness Questionnaire for Everyone (PAR-Q+)

• Regularly engaged in endurance exercise (running, cycling, swimming) for a minimum of three years, a weekly training volume of 5-10 hours, and a maximal oxygen uptake of 45.00 ml·kg-1·min-1 or higher as determined by completion of VO2peak assessment (Visit #1).

Exclusion Criteria:

• Recent musculoskeletal injuries or surgeries

• Any chronic illness that requires continuous medical care

• Current incarceration, cognitive impairment or inability to provide consent

• Present or past use of performance-enhancing drugs

Related Conditions & MeSH terms

• Dietary Supplementations

Intervention

Dietary Supplement:
• Carbohydrate
Participants have a one in three chance of consuming a carbohydrate beverage between two bouts of high-intensity exercise.
• Carbohydrate-Protein
Participants have a one in three chance of consuming a carbohydrate-protein beverage between two bouts of high-intensity exercise.
• Placebo
Participants have a one in three chance of consuming a placebo beverage between two bouts of high-intensity exercise.

Locations

Country	Name	City	State
United States	University of Central Florida	Orlando	Florida

Sponsors (1)

Lead Sponsor	Collaborator
Erica Goldstein

Country where clinical trial is conducted

United States, 

References & Publications (3)

Alghannam AF, Jedrzejewski D, Bilzon J, Thompson D, Tsintzas K, Betts JA. Influence of Post-Exercise Carbohydrate-Protein Ingestion on Muscle Glycogen Metabolism in Recovery and Subsequent Running Exercise. Int J Sport Nutr Exerc Metab. 2016 Dec;26(6):572 — View Citation

Berardi JM, Price TB, Noreen EE, Lemon PW. Postexercise muscle glycogen recovery enhanced with a carbohydrate-protein supplement. Med Sci Sports Exerc. 2006 Jun;38(6):1106-13. — View Citation

McCarthy DG, Spriet LL. Performance Effects of Carbohydrate Ingestion Between Bouts of Intense Aerobic Interval Exercise. Int J Sports Physiol Perform. 2020 Feb 1;15(2):262-267. doi: 10.1123/ijspp.2019-0239. Epub 2019 Jun 12. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Time to Exhaustion (TTE)	Participants cycle for as long as possible at 90% of peak power output (watts)	Visit #3 (Day 7)
Secondary	Heart Rate Variability (HRV)	R-R intervals recorded via a heart rate monitor and Elite HRV will be downloaded and analyzed using a laptop with commercially available HRV analysis software. Root mean square of the successive differences of R-R intervals (RMSSD) values will be recorded during the 90% TTE and then post-exercise every 5 min (end of TTE, 5min, 10min, 15min, 20min, 25min, 30min).	Visit #3 (Day 7)
Secondary	Sweat Rate (SR)	Sweat rate will be determined based on the difference between pre-and post-weight changes for each bout of exercise, the amount of fluid consumed during the recovery period, and total exercise time in minutes.	Visit #3 (Day 7)