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Dietary Supplement clinical trials

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NCT ID: NCT05984771 Completed - Diabetes Mellitus Clinical Trials

Efficacy and Safety of the Combination of Ten Elements for 6 Months in Patients With Diabetic Neuropathy : A Pilot Study

Start date: January 10, 2021
Phase: N/A
Study type: Interventional

To investigate the efficacy of Superoxide Dismutase (SOD, 70 UI), Palmitoylethanolamide (PEA, 300 mg) Alpha Lipoic Acid (ALA, 300 mg), vitamins B6 (1.5 mg), B1 (1.1 mg), B12 (2.5 mcg), E (7.5 mg), Nicotinamide (9 mg) and minerals (Mg 30 mg, Zn 2,5 mg) in one tablet in patients with Diabetic Neuropathy (DN).

NCT ID: NCT05963594 Completed - Dietary Supplement Clinical Trials

To Evaluate the Post-Prandial Metabolic Effects of Oligomalt in Adults With T2D and in HAO

LORIS-02
Start date: January 23, 2023
Phase: N/A
Study type: Interventional

The goal of this mechanistic, exploratory study is to compare the effectiveness of Oligomalt to Glucidex 40 after eating in adults with Type 2 Diabetes (T2D) and in otherwise healthy adults with overweight or obesity (HAO).

NCT ID: NCT05880186 Completed - Dietary Supplement Clinical Trials

Influence of the Time of Day in the Effect of Caffeine on Maximal Fat Oxidation During Exercise in Women

CIRCAF_WOM
Start date: February 9, 2021
Phase: N/A
Study type: Interventional

Caffeine is a natural stimulant with well-recognized metabolic benefits, however, there is a lack of studies investigating the time-of-day caffeine influence to enhance fat oxidation in women. The aim of this study was to evaluate the influence of the time of the day on the effect of caffeine on maximal rate of fat oxidation during aerobic exercise in women.

NCT ID: NCT05337527 Completed - Placebo Clinical Trials

Neuromuscular Responses to Acute Beetroot Ingestion in Women Older Adults

BEET_ELDERLY
Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Beetroot juice supplementation has shown the capacity for provoking different physiological effects (e.g. vasodilation and muscle contraction increments). However, the effects of beetroot juice ingestion on neuromuscular performance in women older adults are barely studied. In this randomized placebo-controlled study, we investigated the effects of beetroot acute supplementation in improving neuromuscular performance in women older adults

NCT ID: NCT05210244 Completed - Dietary Supplement Clinical Trials

Acute Beetroot Juice Supplementation in Amateur Climbers

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

Whereas beetroot juice (BJ) supplementation is shown to increase physical performance in endurance activities, its benefits in neuromuscular function and strength performance has been barely studied. In this cross-over randomized placebo-controlled study, we investigated the effects of BJ acute supplementation in improving neuromuscular performance in amateur climbers

NCT ID: NCT04877366 Completed - Dietary Supplement Clinical Trials

Evaluate Effects of Sprinkled Format REDUCOSE in a Carbohydrate-rich, Mixed Meal on Post-prandial Glycemia

Stardust
Start date: July 21, 2021
Phase: N/A
Study type: Interventional

This is a mechanistic, single-center, double-blind, placebo- and active-controlled, three-time-period, crossover study to evaluate the effect of sprinkled format REDUCOSE compared to placebo (double-blind; confirmative) and active control (open-label; acarbose - explorative) on post prandial glycemia in Asian patients with type 2 diabetes.

NCT ID: NCT04832412 Completed - Stress Clinical Trials

Effect of BrainPhyt, a Microalgae Based Ingredient on Cognitive Function in Healthy Older Subjects

PHAEOSOL-THREE
Start date: April 1, 2021
Phase: N/A
Study type: Interventional

In developed countries, the acceleration of the general population ageing has been widely described for decades, involving changes in public health policies. Among the health issues arising from this demographic change, the maintenance of cognitive function will be a major challenge in the next years, both in societal and economic terms. In this regard, some pharmacological and behavioural (e.g. physical activity, social involvement, intellectually demanding activities) preventive approaches have been evaluated to improve cognitive function with ageing. Among them, dietary interventions showed a potential interest to prevent cognitive decline during ageing. In this sense, there is a growing interest to find ecological solutions and to meet major societal challenge the use of microalgae as molecule of interest sources is a recent promising approach. Marine environments harbour a huge biological diversity of microalgae that represents a large source of almost untapped bioactive compounds. This biodiversity comprises 200,000 to 2 million species with about 35,000 which are described and 15,000 maintained in culture collections. Microalgae are able to produce bioactive molecules, such as pigments, fatty acids, peptides and sterols. Some of these compounds are unique and specifically found in the marine environment and they could be increasingly used as natural bioactive products for targeted applications. Fucoxanthin is one of the major carotenoid found in microalgae well known for its neuroprotective effect but to our knowledge no human studies were realized. Thus the objective is to evaluate, in healthy older adults, the effect of a 24-week period of daily supplementation of high and low BrainPhyt, doses on cognitive function parameters (Spatial Working Memory scores, Attention and vigilance, episodic memory, executive function), stress, mood, sleep quality and biomarkers.

NCT ID: NCT04761406 Completed - Clinical trials for Overweight and Obesity

Microalgae Extract Phaeosol Combined to Exercise in Healthy Overweight Women : Efficacy on Body Weight Management

PHAEOSOL-ONE
Start date: April 26, 2021
Phase: N/A
Study type: Interventional

PhaoeSOL (Microphyt, Baillargues, France) is a microalgae-based nutritional ingredient developed with a patented production process that has New Dietary Ingredient (NDI) status from the FDA (#1120). It is an extract of the microalgae Phaeodactylum tricornutum standardized to 2.0% Fucoxanthin (FX) content by adding a food grade medium-chain triglyceride (MCT)-oil and a tocopherol-rich (Vitamin E) extract (0.5 % w:w). PhaeoSOL is intended for use as a source of the naturally occurring carotenoid, fucoxanthin, in food supplement products for the general population at levels not to exceed 437 mg/person/day for a maximal duration of 30 days of PhaeoSOL (equivalent to 10 mg fucoxanthin/person/day). Prior studies suggest that marine algae and Fucoxanthinol may have anti-obesity, lipid lowering, and glucose management enhancing properties. The purpose of this proof of concept pilot study is to examine whether dietary supplementation of PhaoeSOL enhances the benefits of women participating in an exercise and weight management program.

NCT ID: NCT04639726 Completed - Dietary Supplement Clinical Trials

A Study to Evaluate the Effects of Pre-Meal Whey Protein Microgels Administration on Post-Prandial Glycemic Response.

Start date: September 28, 2020
Phase: N/A
Study type: Interventional

This is a mechanistic, randomized, investigator-blinded, placebo-controlled, single-center, crossover study designed to evaluate the effects of premeal administration of whey protein microgels compared to placebo on postprandial glycemia in patients with type 2 diabetes.

NCT ID: NCT04210531 Completed - Dietary Supplement Clinical Trials

Beetroot Juice Supplementation in Basketball Players

Start date: June 9, 2019
Phase: N/A
Study type: Interventional

Whereas beetroot juice (BJ) supplementation is shown to increase physical performance in endurance activities, its benefits in team sports has been barely studied. In this randomized placebo-controlled study, we investigated the effects of BJ acute supplementation in improving neuromuscular performance and physical match activity in basketball.