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Clinical Trial Summary

The goal of this clinical trial is to to test the effects of dietary composition, on the rhythms of food intake and appetite regulation, and rhythms of energy expenditure. Participants will: complete 2 field-based dietary interventions be provided with standard meals record daily food intakes in a real-time manner complete 2 inpatient stays be provided with standard meals have frequent blood draws provide urine, saliva, stool and rectal swab samples


Clinical Trial Description

Obesity is an ongoing epidemic and a serious public health problem. Recent insights into the involvement of the circadian system (i.e., an internal biological rhythm) in energy expenditure and appetite control offer a new perspective to understand the relationship between dietary composition and weight management. Particularly, dietary composition may impact whole-body physiology in part through changes in the circadian system. The study protocol is designed to test the effects of dietary composition, on the rhythms of food intake and appetite regulation, and rhythms of energy expenditure. This study seeks to understand the relationship between dietary composition and weight control in order to lay the groundwork for evidence-based dietary intervention to combat obesity. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05800990
Study type Interventional
Source Brigham and Women's Hospital
Contact Jingyi Qian, PhD
Phone 6175257423
Email jqian@bwh.harvard.edu
Status Not yet recruiting
Phase N/A
Start date January 1, 2024
Completion date August 31, 2027

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