Clinical Trials Logo

Clinical Trial Summary

The prevalence of type 2 diabetes (T2D) is increasing worldwide, with ~380 M currently suffering from this chronic, debilitating disease. T2D is characterized by high blood glucose levels in the mornings and after meals. The largest hyperglycemic spike often occurs after breakfast. Targeting this meal may be a simple, feasible strategy to improve glycemic control and reduce risk for diabetes complications. It is hypothesized that consuming a low carbohydrate high fat (LCHF) breakfast for 3 months, when compared to a standard low-fat breakfast will improve blood glucose control, increase satiety and improve body composition in people with T2D. This information will test whether the simple dietary strategy of limiting carbohydrates at breakfast could help in managing T2D.


Clinical Trial Description

A 3-month parallel-group randomized controlled trial will be conducted. Eligible participants will be randomized to either the Low-carb High-fat breakfast (LCHF, n=41) or a low-fat "standard care" control breakfast (CTL, n=41), to be consumed daily for a period of 3 months. Due to COVID-19 pandemic, this study was adapted to be conducted remotely through video/telephone conference meetings between participants and study staff, along with mailing of study materials before and after the intervention for remote data collection. Each group will be provided with a menu of 8 LCHF breakfasts or 8 CTL breakfasts from which to choose each morning. Breakfast options (designed by a registered dietitian) will be controlled in macronutrient content and calories (~400-500 kcal), but allow for personal preference and autonomy to promote adherence. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04550468
Study type Interventional
Source University of British Columbia
Contact
Status Completed
Phase N/A
Start date October 1, 2020
Completion date June 30, 2022

See also
  Status Clinical Trial Phase
Completed NCT04025099 - Internal Cues Versus External Cues for Eating and Activity N/A
Recruiting NCT06094049 - Acceptability of Folic Acid and Vitamin B12 Fortified Meals
Completed NCT03720314 - Microbiota Profiling in IBS
Completed NCT03334266 - Preventing Early Childhood Obesity, Part 2: Family Spirit Nurture, Prenatal - 18 Months N/A
Recruiting NCT02894931 - Effects of Dietary Interventions on Serum and Macrophage Atherogenicity N/A
Completed NCT02559076 - The Eat Right Emirates Healthy Lifestyle Study N/A
Completed NCT05502445 - The Nutritionist's Educational Intervention on the Protein Intake in Hospitalized Elderly People N/A
Active, not recruiting NCT04308473 - Analysis of MicroBial Metabolites After Eating Refined Food N/A
Completed NCT04082247 - Healthy Children 2021 Study in Childcare Centers N/A
Recruiting NCT05157815 - Study to Investigate the Effect of Dietary Fibre Supplementation on Long-term Glucose Control in Prediabetic Subjects N/A
Active, not recruiting NCT05607745 - Dietary Counseling Coupled With FMT in the Treatment of Obesity and NAFLD - the DIFTOB Study N/A
Completed NCT06045845 - Effects of Beet Juice and Diet in Female Rowers N/A
Completed NCT03775889 - Engaging School and Family in Navajo Gardening for Health N/A
Not yet recruiting NCT02910128 - Childhood Obesity Prevention Trough Education Innovation in Primary School: A Quasi-experimental Trial N/A
Completed NCT02572479 - Evaluating the Potential of the Diet as Disease Modifier in Amyotrophic Lateral Sclerosis (JERN_ALS)
Completed NCT03189979 - Club Fit: Physical Activity and Healthy Eating at an After School Program N/A
Completed NCT02102763 - Greek Childhood Obesity (GRECO) Study N/A
Completed NCT04632771 - Nutritional Status and Bouillon Use in Northern Ghana
Recruiting NCT03500458 - Impact of Sleep Extension in Adolescents N/A
Completed NCT03673267 - Nutricity: A Pilot Study to Improve Parental Nutrition Literacy N/A