Exercise Clinical Trial
Official title:
The Effects of Acute Caloric Deprivation on Odour Identification and Food Reward
The purpose of this study is to determine how the modality of energy depletion can differently impact appetite hormones, ad libitum food intake, food hedonics, and olfaction.
The objectives of the current randomized controlled study were to examine how the modality
of an acute 3 day isocaloric -25% energy depletion by dieting alone or by aerobic exercise
alone differently impacts appetite and appetite-related hormones, ad libitum energy intake
(EI), food hedonics and food reward, and olfaction. It was hypothesized that independent of
modality of depletion, that relative to the control, there would be increased ad libitum
feeding and food reward, improvements in smell performance, and a decline in fasting leptin
and increase in fasting total ghrelin. It was also hypothesized that the increased food
reward would prove to be a predictor of ad libitum EI and that relative to the depletion by
aerobic exercise alone, the depletion by diet alone would produce greater compensatory
increases in appetite, ad libitum EI, and food reward.
Statistics
To test for differences in body weight, plasma hormone concentrations, relative-reinforcing
value of food (RRVF), and olfaction across each condition of the study, repeated measures
ANOVA controlling for day 1 as a covariate was employed. Pairwise comparisons at day 4 using
Sidak adjustment to account for multiple comparisons are reported when the ANOVA was
significant. One way repeated measures ANOVAs with Sidak adjustments for multiple
comparisons were used to test for differences in variables measured only at day 4: body
composition (fat mas, %Fat, and fat free mass), appetite, palatability, and ad libitum EI.
;
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Basic Science
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