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Plasma, Urine and Tear Omics Changes in Different Diets

Diet, Healthy Clinical Trial

Official title:
Plasma, Urine and Tear Omics Changes Based on Protein and Metabonomics Technology in Different Diets and Screening of Healthy Diet Markers

Clinical Trial Summary

The study plans to start in July 2021, and it is expected that 20 healthy people (aged 18-70 years old, BMI 18.5-40kg/m2) will carry out a 5-week intervention and follow-up. Participants will be enrolled in the group through the screening and plan to take regular diet, OGTT, high-fat diet, low-calorie diet and ketogenic diet within 5 weeks. The proteomics and metabolomics indicators of tear, plasma, and urine specimens will be measured at 5 time points at baseline, 30 minutes, 1 hour, 2 hours, and 3 hours for each diet. The correlation of proteomics and metabolomics indicators with classic laboratory parameters (BMI, HDL, LDL, cholesterol, triglyceride levels, and insulin resistance (HOMA-IR)) will be analyzed.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04984642
Study type Interventional
Source Second Affiliated Hospital, School of Medicine, Zhejiang University
Contact Pengfei Shan, MD
Phone +86 13958039665
Email pengfeishan@zju.edu.cn
Status Recruiting
Phase N/A
Start date July 1, 2021
Completion date October 1, 2021
View Details
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