Diaphragm Clinical Trial
Official title:
Effects of Transcutaneous Electrical Phrenic Nerve Stimulation and Transcutaneous Electrical Diaphragmatic Stimulation: a Randomized Controlled Crossover Trial
Transcutaneous electrical phrenic nerve stimulation (TEPNS) and transcutaneous electrical diaphragm stimulation (TEDS) are modalities that use surface electrodes placed on the patients' skin to generate action potentials and contractions of the muscle fibers of the diaphragm. The primary objective will be to evaluate the efficacy of TEPNS and TEDS in healthy adult individuals. Secondary objectives will be to assess the feasibility, safety, and level of discomfort reported by the individual resulting from the application of TEPNS and TEDS.
This crossover trial, single-blind, bicentric study will be conducted at two hospitals. Adult volunteers aged 18 to 60 years, healthy, with a body mass index between 18.5 and 24.9 kg/m2, without a history of previous respiratory diseases, and without contraindications to undergo evaluation or application of the proposed electrical stimulation modalities will be included. Participants' diaphragm muscle will be assessed using ultrasound for variables such as thickness, thickness fraction, and diaphragm mobility. Patients will be randomized using opaque envelope draw prior to evaluation into two distinct experimental moments: 1) "TEPNS" moment - application of the TEPNS protocol; or 2) "TEDS" moment - application of the TEDS protocol. Additionally, data regarding the feasibility and safety of the application of electrical stimulation modalities will be collected. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT03600207 -
The Effect of Diaphragm Muscle Training on Chronic Low Back Pain
|
N/A | |
| Completed |
NCT02916342 -
Interscalene Block Versus Combined Supraprascapular: Axillary Nerve Blocks
|
Phase 4 | |
| Completed |
NCT02801058 -
Ultrasound Evaluation of Changes in Diaphragm Induced by Osteopathic Manipulative Techniques
|
N/A | |
| Completed |
NCT03688724 -
Perioperative Diaphragm Point of Care Ultrasound
|
||
| Completed |
NCT04052230 -
Evolution of Diaphragm Thickness Under Veno-arterial ECMO
|
||
| Recruiting |
NCT03827538 -
Endobronchial Valves Positioning Effects On Diaphragm Function In Patients With Lung Hyperinflation
|
||
| Recruiting |
NCT05965830 -
Comparing Electromyography of the Diaphragm With Ultrasound in Neonates and Children With Respiratory Support
|
||
| Completed |
NCT06086769 -
High Flow Oxygen Therapy Effect on Healthy Subjects
|
N/A | |
| Completed |
NCT03129386 -
Defining the Normal Range for Maximal Sniff Diaphragm Thickening Fraction
|
||
| Completed |
NCT05670327 -
Diaphragmatic Ultrasound and Weaning After Lung Transplant.
|
||
| Recruiting |
NCT06009731 -
Diaphragmatic Speckle Tracking During Spontaneous Breathing Trial
|
||
| Recruiting |
NCT01053182 -
Esophagectomy Associated Respiratory Complications: Ivor-Lewis Versus Sweet Approaches
|
Phase 3 | |
| Completed |
NCT04333186 -
Expiratory Muscle Function in Critically Ill Ventilated Patients
|
||
| Recruiting |
NCT05529641 -
Effects of Diaphragmatic Resistance Training in People With Chronic Neck Pain.
|
N/A | |
| Completed |
NCT06347549 -
The Impact of Diaphragmatic Breathing Instructions and Inspiratory Pressures on Diaphragm Contraction in Healthy Adults
|
||
| Completed |
NCT02725190 -
Effects of Sleep Deprivation on Diaphragm Command During an Inspiratory Endurance Trial in Healthy Volunteers.
|
N/A | |
| Recruiting |
NCT03114384 -
Patient-ventilator Asynchrony During Noninvasive Ventilation Assessed Using Diaphragm Ultrasonography
|
N/A | |
| Not yet recruiting |
NCT06348745 -
Trans Thoracic Ultrasound to Assess Diaphragmatic Function in Stable COPD Versus Bronchial Asthma.
|
N/A |