Laparoscopy Versus Clinical Follow up to Detect Diaphragm Injury

Status Completed

Clinical Trial Summary

Title: A randomized prospective study comparing non operative management with laparoscopic treatment in patients with a diaphragm injury following left thoracoabdominal stab wounds.

Aim of the Study: The aim of this study is to access the clinical outcome of potential occult diaphragm injuries in a group of patients presenting at the Groote Schuur trauma centre with left sided thoracoabdominal stab wounds, if an expectant non operative management course is taken.

Objects of the Study: To obtain the above mentioned aim the study will undertake;

- to do laparoscopy on a group of randomly selected patients with left thoracoabdominal stab wounds to obtain the incidence of occult diaphragm injury.

- to assess the incidence and clinical outcome of delayed diaphragm visceral herniation in the study group.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Diaphragm Injury

Clinical Trial Details

NCT number	NCT01044550
Study type	Interventional
Source	University of Cape Town
Contact
Status	Completed
Phase	N/A
Start date	September 2009
Completion date	October 2014

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT03681275` - Janus Kinase Inhibition to Prevent Ventilator-induced Diaphragm Dysfunction	Phase 2
Completed	`NCT03440593` - Indirect Calorimetry Usage and Effect in Ventilator-free Days and Muscle Thickness in Septic Ventilated Patients	N/A
Completed	`NCT05582642` - Respiratory Muscles After Inspiratory Muscle Training After COVID-19	N/A
Withdrawn	`NCT03132896` - Re-Evaluation of Systemic Early Neuromuscular Blockade and Transthoracic Ultrasound Assessment of the Diaphragm
Completed	`NCT03129217` - The Validity of Maximal Diaphragm Thickening Fraction to Measure Diaphragm Function in Mechanically Ventilated Patients
Recruiting	`NCT05191433` - Effects of Mechanical Ventilation on the Diaphragm in COVID-19 Intensive Care Patients. A Post-mortem Pathology Study
Suspended	`NCT04026217` - Diaphragm Ultrasound as a Powerful Tool in Managing Acute Hypoxemic Respiratory Failure in Hematological Patients
Active, not recruiting	`NCT05041894` - Effect of Body Tilting on Diaphragm Excursion and Thickness in the Stroke Patients With Tracheotomy by Ultrasonography
Completed	`NCT03580720` - Electromyography for Diaphragm Effort	N/A
Not yet recruiting	`NCT05125744` - Effect of Positive End Expiratory Pressure on Diaphragmatic Fraction Assessed Through Ultrasound in Intubated Patient Undergoing Assisted Ventilation
Completed	`NCT03108118` - Diaphragm Injury and Dysfunction During Mechanical Ventilation
Completed	`NCT04854863` - Respiratory Muscles After Hospitalisation for COVID-19
Recruiting	`NCT04937868` - Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients
Recruiting	`NCT05642832` - Feasibility of Reducing Respiratory Drive Using the Through-flow System	N/A
Completed	`NCT05465083` - Feasibility of Transvenous Phrenic Nerve Stimulation for Diaphragm Protection in Acute Respiratory Failure	N/A
Completed	`NCT04904731` - Effects of Body Position on Diaphragmatic Activity in Patients Requiring Noninvasive Ventilation for Acute Respiratory Failure COVID-19 Related
Recruiting	`NCT05194631` - Evaluation of the Regeneration Capacity of Satellite Cells From the Quadriceps Compared to That of the Diaphragm	N/A
Active, not recruiting	`NCT03303040` - Effect of Diaphragm Stimulation During Surgery	N/A
Active, not recruiting	`NCT04103996` - Incidence, Risk Factors and Outcomes of Diaphragm Dysfunction After Lung Transplantation
Completed	`NCT03612583` - Lung and Diaphragm-Protective Ventilation by Means of Assessing Respiratory Work	N/A