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Dialysis Related Complications clinical trials

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NCT ID: NCT03082625 Not yet recruiting - Clinical trials for Chronic Kidney Diseases

Topical Magnesium and Muscle Cramps in Dialysis Patients.

Start date: May 1, 2017
Phase: Phase 2
Study type: Interventional

Oral magnesium supplementation has been widely used in the treatment of muscle cramps. Muscle cramps are common in dialysis patients but are not satisfactorily prevented by oral magnesium. Transdermal administration of magnesium has been promoted as a potential treatment for muscle cramps but this has not been investigated rigorously. We aim to evaluate the effectiveness of transdermal magnesium supplementation in reducing cramp frequency and severity. We will recruit current haemodialysis patients who suffer from muscle cramps into a randomised, placebo-controlled, cross-over design trial. Each intervention period will last 8 weeks with a 4-week washout period in between. We will measure muscle cramp frequency, duration and severity as the primary outcomes.