Clinical Trials Logo

Clinical Trial Summary

This research aims to assess the effect of low versus high dialysate sodium concentration during hemodialysis on dialysis recovery time


Clinical Trial Description

Chronic kidney disease (CKD) is a general term for heterogeneous disorders affecting the structure and function of the kidney. The variation in disease expression is partly related to the cause, pathology, severity and the rate of progression. Fatigue is a well-known and frequent symptom in HD patients with a reported association with the decrease in health-related quality of life commonly found in this population. The prevalence of fatigue ranges from 60% to as high as 97% in patients on long-term renal replacement therapy. Despite this fact, health care providers are still unaware of both its presence and severity. Several methods have been proposed as a way to assess post-HD fatigue with the "time to recover (minutes) from HD" being one of them. Lindsay et al.assisted patients' responses to the single open-ended question, "How long does it take you to recover from a dialysis session?". Although post-HD fatigue commonly exists in dialysis patients, it is usually underestimated by physicians. For this reason, appropriate and early identification of symptoms and associated factors might improve the patient's quality of life. Rayner et al. found that dialysate Na was inversely associated with DRT where lowering the Na concentration in the dialysate (to 140 mEq/L) was linked to a longer DRT. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05418647
Study type Interventional
Source Alexandria University
Contact Mohamed Mamdouh Elsayed, MD
Phone 00201068055103
Email dr_mohamedmamdouh87@yahoo.com
Status Not yet recruiting
Phase N/A
Start date July 15, 2023
Completion date October 15, 2023

See also
  Status Clinical Trial Phase
Completed NCT06022835 - Chlorhexidine Gluconate-gel Dressing for Exit Site Infection in Peritoneal Dialysis N/A
Not yet recruiting NCT05939505 - The Effect of Sujok Therapy on Symptom Burden and Comfort Level in Patients Undergoing Hemodialysis Treatment N/A
Completed NCT05307601 - Immune Response Following COVID-19 in Hemodialysis Patients
Active, not recruiting NCT05287204 - Critical Illness Myopathy and Trajectory of Recovery in AKI Requiring CRRT
Recruiting NCT06141798 - Twice vs Thrice Weekly Incident Hemodialysis in Elderly Patients N/A
Recruiting NCT04954690 - Structured Program of Exercise for Recipients of Kidney Transplantation N/A
Not yet recruiting NCT05586854 - Multicenter Study on Dialysis Modalities for End-stage Chronic Renal Failure Patients With Heparin-induced Thrombocytopenia N/A
Completed NCT05382468 - Effectiveness of Intradialytic Exercise on Reduction in Fatigue and Muscle Cramps N/A
Recruiting NCT05105503 - Dialysis Access Monitoring Using a Digital Stethoscope-Based Deep Learning System
Recruiting NCT06374537 - Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients. N/A
Not yet recruiting NCT06360302 - Plasma Biomarkers of Muscle Metabolism During Exercise to the Assessment of Insulin Resistance in CKD Dialysis Patients N/A
Completed NCT05564676 - Flaxseed Oil and Pomegranate Extract on Inflammation, Lipid Profile and Nutritional Status of Hemodialysis Patients N/A
Completed NCT05214872 - The Impact of Selected Factors on the Cardiovascular System in Chronic Kidney Disease
Not yet recruiting NCT05966116 - Sodium Accumulation Study in Haemodialysis: Brain Study
Recruiting NCT06153888 - ULtrafiltration-Rate Induced CArdiac Strain (ULRICA) - Study N/A
Completed NCT04285775 - A Novel Device for Surveillance of Vascular Access Sites for Bleeding
Not yet recruiting NCT06123806 - Factors Affecting Dialysis Associated Fatigue
Recruiting NCT05096195 - PRevEnting FracturEs in REnal Disease 1 Phase 4
Completed NCT04274556 - Recovery Time and Affecting Factors in Hemodialysis Patients
Recruiting NCT05306964 - Restrictive Versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury N/A