The Objective Assessment and Characteristics of Dry Nose From Clinical Perspective

Diagnostic Self Evaluation Clinical Trial

Official title:

The Objective Assessment and Characteristics of Dry Nose From Clinical Perspective

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05401344
• Other study ID #: V 1.0
• Status: Completed
• Start date: December 11, 2018
• Est. completion date: October 31, 2021

Study information

• Verified date: December 2018
• Source: Beijing Tongren Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

In the present study, we propose objective diagnostic criteria for dry nose (DN) and investigate its characteristics. Questionnaires were completed by each participant during recruitment to record demographic data. DN test strips were used to evaluate the severity of DN at five time points and allergic status was assessed based on serum sIgE levels. Nasal secretions were collected and vasomotor rhinitis was diagnosed using the cold dry air test. The diagnosis of allergic rhinitis (AR) was based on the criteria of the Allergic Rhinitis and its Impact on Asthma consensus statement. Data are expressed as median and interquartile range, unless otherwise specified. Statistical significance was set at P < 0.05. The reference range (RR) of the 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles were determined for each test strip length at each time point. This study aimed to investigate the characteristics of and propose objective diagnostic criteria for DN.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 120
• Est. completion date: October 31, 2021
• Est. primary completion date: July 24, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 23 Years to 73 Years

Eligibility

Inclusion Criteria:

• Clinical diagnosis of dry nose patients.

Exclusion Criteria:

• chronic rhinosinusitis and/or nasal polyposis, allergic fungal rhinosinusitis, immunological disease, tumor patients, pregnant women.

Related Conditions & MeSH terms

• Diagnostic Self Evaluation

Intervention

Diagnostic Test:
• test strips,sponges and cold dry air test
Test strips were used to evaluated the degree of dry nose, sponges were used to obtain the nasal secretion and cold dry air test was used to making diagnosis of vasomotor rihinitis.

Locations

Country	Name	City	State
China	Yifan Meng	Beijing	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Beijing Tongren Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The length of the test strip.	We propose that the diagnostic criterion for DN is a strip length less than 17.0 mm at 5 min.	5 minutes