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Diagnostic Self Evaluation clinical trials

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NCT ID: NCT05458089 Completed - Clinical trials for Diagnostic Self Evaluation

18F-FDG PET/CT in the Diagnosis of Tuberculous Pericarditis

Start date: January 1, 2015
Phase:
Study type: Observational

A total of 11 patients confirmed with tuberculous pericarditis were enrolled in this study to analyze the diagnostic value of 18F-FDG PET/CT for tuberculous pericarditis.

NCT ID: NCT05401344 Completed - Clinical trials for Diagnostic Self Evaluation

The Objective Assessment and Characteristics of Dry Nose From Clinical Perspective

Start date: December 11, 2018
Phase:
Study type: Observational

In the present study, we propose objective diagnostic criteria for dry nose (DN) and investigate its characteristics. Questionnaires were completed by each participant during recruitment to record demographic data. DN test strips were used to evaluate the severity of DN at five time points and allergic status was assessed based on serum sIgE levels. Nasal secretions were collected and vasomotor rhinitis was diagnosed using the cold dry air test. The diagnosis of allergic rhinitis (AR) was based on the criteria of the Allergic Rhinitis and its Impact on Asthma consensus statement. Data are expressed as median and interquartile range, unless otherwise specified. Statistical significance was set at P < 0.05. The reference range (RR) of the 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentiles were determined for each test strip length at each time point. This study aimed to investigate the characteristics of and propose objective diagnostic criteria for DN.

NCT ID: NCT05099731 Completed - Periodontitis Clinical Trials

Diagnostic Accuracy of Matrix Metalloproteinase-8 Test for the Discrimination of Periodontal Health and Disease

Start date: October 10, 2021
Phase:
Study type: Observational

The application of point-of-care test with oral fluid-based biomarkers assisting in early-detection of gum disease is highly needed. Recently, a commercially available active Matrix metalloproteinase-8 (aMMP-8) point-of-care test (POCT) for detecting the risk of gum disease has been developed. Currently, there is a paucity of research to assess the performance of aMMP-8 POCT using different oral fluid sampling methods. This study will evaluate the accuracy of aMMP-8 POCT for discriminating periodontal health from disease in saliva and oral rinse.The information obtained from this study may help us understand better which sample is superior for the early detection of gum disease.

NCT ID: NCT03883230 Completed - Diabetic Foot Clinical Trials

Wound Infection Detection Evaluation, WIDE

WIDE
Start date: July 27, 2017
Phase:
Study type: Observational

Chronic wounds, such as diabetic foot ulcers, place a huge burden on healthcare systems and can lead to complications with high morbidity, particularly if the wound if infected. In parallel, there is pressure to reduce the use of antibiotics in order to minimise the risk of antimicrobial resistance. The Glycologic wound detection kit (GLYWD) is a point-of-care test, designed to provide guidance to clinical staff as to whether a chronic wound is infected or not. In this prospective cohort study the premise of this mode-of-action is evaluated. GLYWD will be applied in conjunction with clinical opinion and microbiological testing to determine if there is concordance between the different diagnostic approaches, and if applicable how they may differ in certain patients' wounds.

NCT ID: NCT03246633 Completed - Clinical trials for Diagnostic Self Evaluation

Perceptual Expertise Training for Triage of Moles

Start date: August 10, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to assess a novel educational mobile and online application which will use images of pigmented skin lesions with question prompts to train future medical providers to more accurately detect malignant lesions. The hypothesis of this study is that this new educational tool will result in higher melanoma detection rates among future providers.

NCT ID: NCT03224910 Completed - Clinical trials for Diagnostic Self Evaluation

Diagnostic Efficiency of Touch Imprints Versus Smears

Start date: July 18, 2017
Phase:
Study type: Observational [Patient Registry]

Cytopathologists work along with radiologist in the diagnosis of lesions. Rapid on site interpretation (ROSE) of fine needle aspiration (FNA) smears of radiologically suspicious lesions is a common clinical practice. In the last years, the investigators have seen trend towards needle core biopsies of radiologically suspicious lesions. The investigators want to analyze the challenges of rapid on site interpretation of touch imprints (TI) of needle core biopsies (NCB) versus fine needle aspiration smears.

NCT ID: NCT02513225 Completed - Drug Use Clinical Trials

Trial of an Adapted STD Screening and Risk Reduction Intervention

Start date: July 2015
Phase: N/A
Study type: Interventional

The goal of this research study is to evaluate the impact of a paraprofessional-delivered, culturally adapted, evidence-based intervention (EBI) on sexually transmitted disease (STD), substance use and poor mental/emotional health among American Indians (AI) through a Randomized Controlled Trial (RCT). These intertwining risks have produced marked disparities and have unique cultural and social determinants in Native communities. If aims are achieved, scientific knowledge and community-based practice will be advanced in areas vital to AI communities, and to STD and drug prevention science. Prior to this study, the investigators applied findings from research protocol (IRB#00005929) and adapted a brief intervention to reduce risk and increase protective behaviors for STDs, HIV/AIDS, substance use and poor mental/emotional health, and to promote STD screening. The specific aim of the current study is to compare the efficacy of the adapted brief intervention vs. a comparison condition on participants' condom use, STD screening and treatment-seeking behaviors, substance use and emotional/mental health outcomes at 3 and 6 months post-intervention.

NCT ID: NCT02162043 Completed - Glaucoma Clinical Trials

Development and Evaluation of a Self-administered/Assisted Visual Field Screening Tool for Glaucoma

Start date: November 2014
Phase:
Study type: Observational

This project aims to evaluate a self-administered screening test for glaucoma, the second largest cause of blindness in the western world. New approaches to glaucoma screening are needed because a significant number of patients first present to hospitals with advanced-stage glaucoma and late presentation is associated with a much higher risk for future blindness. This project will develop a new user-friendly visual field test that will be made available through the internet for self-testing. It will conduct both hospital-based and community-based clinical trials to establish benefits and costs of this new test.

NCT ID: NCT01799577 Completed - Clinical trials for Diagnostic Self Evaluation

Comparison of 2-Dimensional and 3-Dimensional Laparoscopic Visions

Start date: January 2013
Phase: N/A
Study type: Observational

This study tests the hypothesis that use of the 3-D laparoscopic vision system (Viking Systems, La Jolla, CA) can significantly improve technical ability on a complex laparoscopic tasks in an experimental model.

NCT ID: NCT01211873 Completed - Clinical trials for Central Nervous System Diseases

Safety and Efficacy Evaluation of DOTAREM® in MRI of Central Nervous System (CNS) Lesions

SENTIO
Start date: September 2010
Phase: Phase 3
Study type: Interventional

The purpose of this study is to look at the safety (what are the side effects)and efficacy (how well does it work) of Dotarem® when used in taking images of the brain / spine. The results will be compared to the results of MRI taken without Dotarem.