Autonomic Phenotype Before & After Akt Inhibition

Clinical Trial Summary

Some Akt inhibitors have produced functional cardiovascular effects such as marked hypotension that may limit their clinical benefit. There are no current data on whether this autonomic failure presents in humans at clinically used doses. We will test the hypothesis that Akt inhibition causes an acute decrease in sympathetic tone and lowers blood pressure.

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NCT number	NCT01593579
Study type	Observational
Source	Vanderbilt University
Contact
Status	Withdrawn
Phase	N/A
Start date	May 2012
Completion date	May 2016

Autonomic Phenotype Before and After Akt Inhibition

Clinical Trial Summary

Clinical Trial Description

Study Design

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