Ovarian Neoplasms Clinical Trial
Official title:
Evaluation and Implementation of New Biomarkers and Algorithms for Diagnosis of Ovarian Cysts/Tumors in the Pelvis
This study evaluates the biomarkers CA125 and HE4 and the algorithms RMI and ROMA on a normal
population in the western region of Sweden. The aim is to improve diagnosis of ovarian
cancer.
If the investigators observe a clear improvement in the early diagnosis of EOC, the
investigators aim to implement the best strategy for all patients with suspected pelvic tumor
mass in the western region of Sweden.
The investigators are currently using CA125 and RMI in diagnosing patients with a pelvic
cyst/tumor and referring them to tertiary centers for surgery in the western region of
Sweden. The diagnostic accuracy is unsatisfying why the investigators are evaluating HE4 and
ROMA as a complement, in combination or separately to improve diagnostic accuracy.
The trial is based on a normal population cohort of patients included at all the hospitals in
the region. The patients were included before surgery and the biomarkers analysed on serum
samples withdrawn preoperatively.
If the investigators observe a clear improvement in the early diagnosis of EOC, the
investigators aim to implement the best strategy for all patients with suspected pelvic tumor
mass in the western region of Sweden.
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