Diabetic Clinical Trial
Official title:
In Vivo Study of the Relationship Between Surface Roughness of a Dental Restorative Material and Biofilm Formation
In this study we intend to find out the pattern of biofilm accumulation in vivo on various
surface finishings.
Our intention is to prepare Polymethylmetacrylate squers on orthodontical brackets,then
prepare the surface of the sample and measure the surface roughness with a profilimeter and
get the mean value in Ra units, then place the brackets on lower premolars and molars for 12
hours, remove them and examine the biofilm formed with confocal scanning microscope.
Several studies in the past to assess the effects of surface roughness on the amount of
plaque accumulation in vitro, whereas only few performed a modern in vitro assessment of the
plaque accumulation. In this study we intend to find out the pattern of biofilm accumulation
in vivo on various surface finishings.
Our intention is to prepare Polymethylmetacrylate squers on orthodontical brackets,then
prepare the surface of the sample and measure the surface roughness with a profilimeter and
get the mean value in Ra units, then place the brackets on lower premolars and molars for 12
hours, remove them and examine the biofilm formed with confocal scanning microscope.
Statistical evaluation of pilot study determined the need to perform this research on
twelve(12) candidates. It is our intention to check two materials in each candidate:
composite resin and polymethylmetacrylate.
;
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind, Primary Purpose: Prevention
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