Prevalence of Diabetic Retinopathy in Type 2 Diabetic Patients

Status Not yet recruiting

Clinical Trial Summary

To determine the stage of Diabetic Retinopathy (DR) and the presenting symptoms at the time of ophthalmological examination of diabetic individuals .

Clinical Trial Description

Diabetic retinopathy (DR) is the main cause of decreased vision and blindness in patients with diabetes throughout the world . In Egypt, the estimated prevalence of diabetes mellitus (DM) is expected to rise from 5-10% in the 1990s to>13% of the population over 20 years old by 2025 . The estimation of the prevalence of diabetic retinopathy (DR) is challenging due to the great variation in the study populations, methodologies, and grading schemes . Globally, the prevalence of DR and diabetic macular edema (DMO) is expected to rise from the estimates for the period 2015-2019 (27%) due to the expected increase in the life expectancy of people living with DM . Diabetic retinopathy is now the 5th leading cause of blindness worldwide and is the main cause of blindness in working population . Blindness due to diabetic retinopathy is more common in type 1 diabetics (4%) than in type 2 (1.6%) . The exact mechanism of how prolonged hyperglycaemia causes retinopathy is still unclear, however studies have shown that prolonged hyperglycaemia alters retinal perfusion thereby disturbing the normal physiological and homeostatic state of the retina, in turn causing retinopathy . Fortunately, much of the visual loss from DR is preventable, and the rates of vision loss from diabetes and DR have steadily declined over the past few decades. Such improvements in visual outcomes for DR are multifactorial, and are due in large part to a combination of better systemic risk factor control, coupled with advances in ocular disease assessment, screening, imaging and treatment in recent years . ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06146699
Study type	Observational
Source	Assiut University
Contact	Abdelrahman M. Abdelhafez, resident
Phone	+201010536251
Email	dr.abdelrahmanhafez@gmail.com
Status	Not yet recruiting
Phase
Start date	December 2023
Completion date	February 2025

View Details

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