The Evaluation of Effect of Sanyinjiao (SP6) Acupressure on Early Diabetic Nephropathy

Diabetic Nephropathy Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02501772
• Other study ID #: 14MMHIS139
• Status: Recruiting
• Phase: N/A
• Start date: September 2014
• Est. completion date: December 2019

Study information

• Verified date: November 2019
• Source: Mackay Memorial Hospital
• Contact: Shih-Ming Chuang
• Phone: 886-919652673
• Email: gopacer[@]hotmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

For diabetic patient with persisted albuminuria under the intensive control on blood pressure and blood glucose, the non-invasive method of acupressure at Sanyinjiao (SP6) is easy to use and significantly effect on albuminuria reduction in patients of diabetic nephropathy.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: December 2019
• Est. primary completion date: August 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 80 Years

Eligibility

Inclusion Criteria:

1. age between 20 and 80 years old;

2. HbA1c was lower than 9% according to the NGSP(National Glycohaemoglobin Standardisation Programme);

3. estimated glomerular filtration rate (eGFR) was more than 60 mL/min/1.73 m2.

Exclusion Criteria:

1. Hyperglycemic crisis, including HHS(hyperglycemic hyperosmolar syndrome) and DKA(diabetic ketoacidosis );

2. Persist diabetes poorly control, Hemoglobin A1c [HbA1c] >9%;

3. Endocrine disorders: such as abnormal function of thyroid, pituitary, and sex glands;

4. heart diseases:such as arrhythmia, myocardial infarction, heart failure, or installed pacemaker;

5. immune and allergic diseases: such as systemic lupus erythematosus and asthma;

6. liver or kidney dysfunction: GOT or GPT(glutamate-pyruvate transaminase ) > 80 IU/L, eGFR<60 (mL/min);

7. pregnant or lactating women;

8. less than 6months postpartum;

9. acute illness, fever, Lower urinary tract infection, NSAID(nonsteroidal antiinflammatory drug) administration;

10. physical dysfunction because of stroke.

Related Conditions & MeSH terms

• Diabetic Nephropathies
• Diabetic Nephropathy
• Kidney Diseases

Intervention

Device:
• acupressure by ankle band

Locations

Country	Name	City	State
Taiwan	Mackay Memerial Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
Mackay Memorial Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	urinary spot albumin creatine excretion ratio (UACR) change		8 week duratoin