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Clinical Trial Summary

Diabetic macular edema (DME) is the main cause of vision loss in patients with diabetes. At present, anti-vascular endothelial growth factor (VEGF) intravitreal injection is the first-line therapy for DME, nevertheless, some patients do not respond well to anti-VEGF agents and often require multiple injections, which increases the psychological and economic burden of patients. Microinvasive pars plana vitrectomy (PPV) has been proven to be safe and effective for refractory DME. However, there are few studies on treatment-naïve DME. The purpose of this study is to explore whether early PPV combined with internal limiting membrane (ILM) peeling can reduce the treatment burden of DME patients, prevent vision loss, and maintain long-term stabilization of diabetic retinopathy.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05728476
Study type Interventional
Source Tianjin Medical University Eye Hospital
Contact Bojie Hu
Phone 13612130943
Email bhu07@tum.edu.cn
Status Recruiting
Phase N/A
Start date March 5, 2024
Completion date September 5, 2026

See also
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