Diabetic Macular Edema Clinical Trial
Official title:
The Use of a Combination of Ozurdex and Eylea Versus Eylea Monotherapy for Diabetic Macular Edema: A Prospective, Comparative Trial
One Year Trial Evaluating Safety of Ozurdex With Eylea (COED)
In this study, the investigators aim to compare the effects of combined use of intravitreal injections of Ozurdex every three3 months and monthly Eylea/aflibercept to monthly intravitreal injections of aflibercept alone as measured by improvement in central subfield thickness from baseline at Week 48 in eyes with center-involving Diabetic Macular Edema and best-corrected visual acuity of 20/40 or worse ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
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Phase 4 | |
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Phase 3 | |
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||
| Terminated |
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|
Phase 3 | |
| Terminated |
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A Trial to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME)
|
Phase 3 | |
| Active, not recruiting |
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This Study Will Evaluate the Efficacy, Safety, and Pharmacokinetics of the Port Delivery System With Ranibizumab in Participants With Diabetic Macular Edema Compared With Intravitreal Ranibizumab
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Phase 3 | |
| Completed |
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A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Intravitreal LKA651 in Patients With Macular Edema
|
Phase 1 | |
| Withdrawn |
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Combination OZURDEX® & EyLea® vs. OZURDEX® Monotherapy in IncompLete-Responders wIth Diabetic Macular Edema
|
Phase 2 | |
| Withdrawn |
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Safety Study of Intravitreal EBI-031 Given as a Single or Repeat Injection to Subjects With Diabetic Macular Edema
|
Phase 1 | |
| Completed |
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Cytokine Levels in Patients With Persistent Diabetic Macular Edema Treated With Triamcinolone Acetonide
|
Phase 2 | |
| Completed |
NCT02979665 -
Changes to the Retina Following Anti-VEGF Treatments for Diabetic Macular Edema
|
||
| Completed |
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Intravitreal Injections of Ziv-aflibercept for Macular Diseases
|
N/A | |
| Completed |
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Outcomes of Diabetic Macula Edema Patients Switched to Aflibercept From Bevacizumab and/or Ranibizumab
|
N/A | |
| Completed |
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Relating Retinal Structural and Functional Parameters to Visual Acuity in Eyes Undergoing Treatment for Diabetic Macular Edema
|
N/A | |
| Terminated |
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Utility of Intravitreal Methotrexate in Diabetic Macular Edema Resistant to Conventional Therapies
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N/A | |
| Completed |
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| Completed |
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Phase 3 | |
| Completed |
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Changes in Ciliary Body Thickness in Patients With Diabetic Macular Edema After Vitrectomy
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N/A | |
| Terminated |
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Phase 2 | |
| Completed |
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Effect of Choline Fenofibrate (SLV348) on Macular Edema
|
Phase 2 |