Diabetic Macular Edema Clinical Trial
Official title:
Ranibizumab in Residual Diabetic Macular Edema Following Previous Anti-VEGF Therapy
This study is designed to confirm that the investigational drug Ranibizumab given by injection into the eye is safe and effective to use in people with diabetic macular edema (DME).
Ranibizumab works by blocking Vascular Endothelial Growth Factor (VEGF), a substance which is
found in eyes with diabetic eye disease and which causes leakage from blood vessels. Several
studies have suggested that eyes with DME may have very high levels of VEGF; therefore,
Ranibizumab may be helpful in blocking VEGF and decreasing DME.
Ranibizumab has been approved by the U.S. Food and Drug Administration (FDA) for the
treatment of wet age-related macular degeneration (AMD) and Retinal Vein Occlusion at the
dose amount of 0.5 mg. Ranibizumab has not been approved for use in subjects with DME.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
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||
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||
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Phase 2 |