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Clinical Trial Summary

This is a phase II study to investigate the safety, preliminary efficacy and pharmacokinetics of SC0062 capsule in patients with chronic kidney disease (diabetic kidney disease and IgA nephropathy)with albuminuria compared to matching placebo.


Clinical Trial Description

This multicenter, randomized, double blind, placebo parallel controlled, 2 cohorts phase II study will contain 2 cohorts: Cohort 1: diabetic kidney disease Cohort 2: biopsy-proven IgAN In each cohort, approximately 120 patients will be randomized to receive SC0062 or placebo daily for 24 weeks. The objective of this study is to evaluate the preliminary efficacy and safety of SC0062 capsules compared to placebo in patients with chronic kidney disease (diabetic kidney disease and IgA nephropathy) with albuminuria who are treated with the maximum tolerated labeled dose renin-angiotensin system inhibitor (RASi). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05687890
Study type Interventional
Source Biocity Biopharmaceutics Co., Ltd.
Contact Jianghua Chen, Prof
Phone 13905814085
Email chenjianghua@zju.edu.cn
Status Recruiting
Phase Phase 2
Start date May 23, 2023
Completion date April 2025

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