Targeting Leukotrienes in Kidney Disease

Status Terminated

Clinical Trial Summary

Diabetic kidney disease (DKD) is associated with significant morbidity and mortality. Identifying new treatments for DKD to be used alone or in combination with other therapies is a high priority. Inflammation plays a key role in DKD and targeting pro-inflammatory lipid mediators called leukotrienes may represent a promising therapy for DKD. The current proposal will investigate whether montelukast, a leukotriene antagonist, reduces proteinuria and improves vascular function and arterial stiffness in patients with DKD.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05362474
Study type	Interventional
Source	University of Colorado, Denver
Contact
Status	Terminated
Phase	Phase 3
Start date	July 1, 2022
Completion date	June 20, 2023

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