Diabetic Kidney Disease Clinical Trial
Official title:
Antiproteinuric Effects of Liraglutide Treatment in Patients With Type 2 Diabetes and Albuminuria: A Randomised, Placebo-Controlled Trial
The purpose of the study is to determine the effect of Liraglutide on albuminuria in type 2 diabetes.
Initial findings point to a clinically significant antiproteinuric effect of liraglutide
treatment, possibly independent from blood pressure reduction. The mechanism behind is
unclear and the magnitude of albuminuria reduction needs to be verified. Antiproteinuric
effects are usually renoprotective and potentially also cardioprotective and may suggest an
additional benefit from liraglutide treatment.
The aim of this study is to evaluate the magnitude of the antiproteinuric effect of
short-term liraglutide treatment (12 weeks) in patients with type 2 diabetes and
albuminuria. In addition, possible mechanisms causing the antiproteinuric effect will be
explored.
;
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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