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Diabetic Foot clinical trials

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NCT ID: NCT02015910 Terminated - Type II Diabetes Clinical Trials

Januvia (Sitagliptin) in Healing Chronic Diabetic Foot Ulcers

Start date: January 2014
Phase: Phase 4
Study type: Interventional

The primary objective of this study is to compare the rate of healing as well as percent of wounds healed in Type II diabetic patients with chronic foot ulcerations receiving sitagliptin versus placebo. The hypothesis for this study is that subjects receiving daily doses of sitagliptin in combination with their regular antihyperglycemic medications will result in increased healing rates as well as a greater number of healed wounds as compared to subjects receiving placebo and their regular antihyperglycemic medications.

NCT ID: NCT01966380 Terminated - Diabetic Foot Ulcer Clinical Trials

Proof of Concept (Design Validation) in Patient With Hard to Heal Wounds Such as Pressure Ulcer, Diabetic Foot Ulcer and Leg Ulcer, Leia

Start date: September 2013
Phase: Phase 2
Study type: Interventional

The purpose of this reseach study is to determine Mölnlycke Health Care´s Leia dressing performance properties is fulfilled and that the dressing is safe when used on wound types such as pressure ulcer, leg ulcer, and diabetic foot ulcer.

NCT ID: NCT01909908 Terminated - Clinical trials for Foot Ulcer, Diabetic

ECM and Blood Components for Wound Healing

Start date: February 2013
Phase: N/A
Study type: Interventional

The Extracellular Matrix (ECM) and Blood Components for Wound Healing feasibility study is a clinical trial approved by Health Canada to study the safety of extracellular matrix (ECM) and autologous blood products in wound healing.

NCT ID: NCT01858545 Terminated - Clinical trials for Foot Ulcer, Diabetic

A Comparative Efficacy Study: Treatment for Non-healing Diabetic Foot Ulcers

Start date: May 2013
Phase: N/A
Study type: Interventional

The primary objective of this study is to assess the effectiveness of MatriStem devices compared to cellular dermal replacement tissue, for the treatment of non-healing diabetic foot ulcers.

NCT ID: NCT01849965 Terminated - Clinical trials for Diabetic Foot Ulcers

Phase 3 Study Evaluating Efficacy and Safety of DSC127 Compared With Vehicle and With Standard-of-care in Diabetic Foot Ulcers

STRIDE 2
Start date: April 2013
Phase: Phase 3
Study type: Interventional

To determine if aclerastide (DSC127) is effective in increasing incidence of complete wound closure up to 10 weeks confirmed 2 weeks later, compared with vehicle (gel without active ingredient) and compared with a standard-of-care gel, in subjects with diabetes mellitus (DM) who have chronic Wagner Grade 1 or 2 diabetic foot ulcers, 0.75 - 6cm2 in size.

NCT ID: NCT01840085 Terminated - Diabetic Foot Ulcer Clinical Trials

Open-Label Study in Diabetic Foot Ulcers (DFU), to Evaluate Safety of 0.03% DSC127 Topical Gel in Chronic Use

STRIDE 5
Start date: December 2015
Phase: Phase 3
Study type: Interventional

To evaluate the safety of topical 0.03% DSC127 Gel when used for one or more continuous treatment periods on a chronic Wagner Grade 1 or 2 foot ulcer(target ulcer) or multiple ulcers in diabetic subjects. The maximum duration of any treatment period is 24 weeks.

NCT ID: NCT01830348 Terminated - Clinical trials for Diabetic Foot Ulcers

Phase III Study to Evaluate Efficacy and Safety of DSC127 in Diabetic Foot Ulcers

STRIDE 1
Start date: February 2013
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine if DSC127 is effective in increasing incidence of complete wound closure at 10 weeks confirmed at a visit 2 weeks later when compared to the vehicle (gel without active ingredient) in subjects with diabetes mellitus (DM) who have chronic Wagner Grade 1 or 2 plantar neuropathic foot ulcers, 0.75 - 6 cm2 in size.

NCT ID: NCT01816672 Terminated - Diabetic Foot Ulcer Clinical Trials

Efficacy of AutoloGel Therapy to Usual and Customary Care in Wagner gd 1 and 2 Diabetic Foot Ulcers.

Start date: April 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if AutoloGel platelet rich plasma used on non healing diabetic foot ulcers Wagner gd. 1 and 2 is more effective then the usual and customary care

NCT ID: NCT01816633 Terminated - Clinical trials for Diabetic Foot Ulcers

Effectiveness of AutoloGel Therapy in Diabetic Foot Ulcers

Start date: October 2013
Phase: N/A
Study type: Interventional

The aim of this trial is to demonstrate the effectiveness of complete wound healing in a prospective, open-label, case-matched cohort trial in which diabetic foot ulcers (DFU) will be treated using AutoloGel and case-matched against a concurrent cohort of patients receiving undefined Usual and Customary Care (UCC) as provided in up to 30 U.S. Wound Registry Research Network (USWRRN) centers.

NCT ID: NCT01764919 Terminated - Clinical trials for Diabetic Foot Infection

[124I]FIAU PET-CT Scanning in Diagnosing Osteomyelitis in Patients With Diabetic Foot Infection

Start date: April 2013
Phase: Phase 2
Study type: Interventional

This protocol will evaluate the sensitivity and specificity of [124I]FIAU as a diagnostic imaging agent for the detection of osteomyelitis in patients with diabetic foot infection.