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Diabetic Foot clinical trials

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NCT ID: NCT04497805 Recruiting - Diabetic Foot Ulcer Clinical Trials

Clinical Study of ALLO-ASC-SHEET in Subjects With Diabetic Wagner Grade II Foot Ulcers

Start date: September 8, 2020
Phase: Phase 2
Study type: Interventional

This is a phase 2 double-blind clinical study to evaluate the efficacy and Safety of ALLO-ASC-SHEET in subjects with Diabetic Wagner Grade II Foot Ulcers, compared to placebo therapy.

NCT ID: NCT04480801 Completed - Diabetic Foot Clinical Trials

The Effect of Thermal Evaluation in Prevention of Diabetic Foot Ulcer

Start date: September 15, 2020
Phase: N/A
Study type: Interventional

The study was planned as a prospective randomized controlled clinical trial to determine the effect of thermal evaluation in preventing diabetic foot ulcers in patients with Type II Diabetes Mellitus (DM).

NCT ID: NCT04467606 Completed - Diabetic Foot Ulcer Clinical Trials

Motivational Interview Based Discharge Planning for Patients With Diabetic Foot Ulcers

Start date: August 1, 2020
Phase: N/A
Study type: Interventional

To evaluate the effectiveness of a discharge planning using the strategy of motivational interviewing among patients with diabetic foot ulcers

NCT ID: NCT04466007 Active, not recruiting - Diabetic Foot Clinical Trials

Safety and Efficacy of Allogeneic Adipose Tissue Mesenchymal Stem Cells in Diabetic Patients With Critical Limb Ischemia

Start date: January 11, 2021
Phase: Phase 2
Study type: Interventional

Phase II national, multicenter, double-blind, randomized, placebo-controlled, phase-3 clinical trial of 3 parallel groups.

NCT ID: NCT04464213 Recruiting - Diabetic Foot Ulcer Clinical Trials

Human Placental Mesenchymal Stem Cells Treatment on Diabetic Foot Ulcer

Start date: November 1, 2020
Phase: Phase 1
Study type: Interventional

This study is designated to: 1. investigate the tolerance and safety of treatment of Human placental mesenchymal stem cells gel on Human diabetic foot ulcer. 2. learn the primary effectiveness of Human placental mesenchymal stem cells gel on Human diabetic food ulcer. 3. study the pharmacokinetics of Human placental mesenchymal stem cells gel on Human diabetic food ulcer.

NCT ID: NCT04460573 Recruiting - Diabetic Foot Ulcer Clinical Trials

Smart Boot Use to Measure Offloading Adherence

Start date: October 19, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to help people with diabetes who develop neuropathic diabetic foot ulcers (DFUs). These ulcers, or sores, if left untreated can increase the chance of amputation. Part of the treatment is to have the person wear a diabetic shoe or boot to help their foot heal. Sometimes people don't wear the boot like they are told. The investigators want to compare three different kinds of diabetic boots to see if they can help make it easier for people to wear their boots as instructed. The investigators will look at three groups of participants: the first group will wear a boot that can't be taken off. The second group will wear a boot that can be taken off, and they will get counseling about how important it is to follow instructions as to how often and when to wear the boot. The third group will wear a "smart" boot, which will interact with the person through a smart watch and smart phone, and give them direct feedback about how they are doing with following their boot wearing prescription. The investigators will also be looking at how much physical activity, like walking, the participants do. And they will compare how well participants sleep and rate their quality of life in the three different boots. The investigators think that giving participants information about how much they are wearing their boot using readily available technology will help them to follow the doctor's directions better, and help their wounds heal faster.

NCT ID: NCT04457752 Recruiting - Clinical trials for Chronic Diabetic Foot Ulcers

Evaluating the Efficacy of Dual Layer Amniotic Membrane (Artacent®)

Start date: September 1, 2020
Phase: Phase 4
Study type: Interventional

A Randomized Controlled Multicenter Clinical Trial, Evaluating the Efficacy of Dual Layer Amniotic Membrane (Artacent®) and Standard of Care versus Standard of Care alone in the healing Chronic Diabetic Foot Ulcers. Multi-center, open label, randomized controlled trial. Study is estimated to require 12 months from first subject enrolled to last subject visit.

NCT ID: NCT04450693 Recruiting - Clinical trials for Diabetic Foot Infection

Cryopreserved Human Umbilical Cord (TTAX01) for Late Stage, Complex Non-healing Diabetic Foot Ulcers (AMBULATE DFU II)

Start date: November 20, 2020
Phase: Phase 3
Study type: Interventional

It is hypothesized that application at 4-week or greater intervals of the human placental umbilical cord tissue TTAX01 to the surface of a well debrided, complex diabetic foot ulcer (DFU) will, with concomitant management of infection, result in a higher rate of wounds showing complete healing within 25 weeks of initiating therapy, compared with standard care alone. This second confirmatory Phase 3 study examines a population of diabetic foot ulcer patients having adequate perfusion, with or without neuropathy, and a high suspicion of associated osteomyelitis in a complex, high grade wound.

NCT ID: NCT04446767 Completed - Clinical trials for Wound Healing Disorder

Photobiomodulation With Polarized Light as Adjunctive Treatment in Diabetic Foot Ulcer

Start date: June 30, 2020
Phase: N/A
Study type: Interventional

Effect of Photobiomodulation With Polarized Light on wound healing and aerobic microflora in Diabetic Foot Ulcer

NCT ID: NCT04440839 Completed - Clinical trials for Peripheral Arterial Disease

Implementation of Telemedicine for Patient With Lower Extremity Wounds

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

The objective of this study is to determine if patients with lower extremity wounds in rural communities who undergo specialty referral through telemedicine have expedited care compared to patients who are treated through standard in person referral.